The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …

Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

Acute respiratory distress syndrome (ARDS) is a complex syndrome of acute lung injury
leading to noncardiogenic pulmonary edema from many causes that is heterogenous in its …

Type 2 immunity mediates protective responses to helminths and pathological responses to
allergens, but it also has broad roles in the maintenance of tissue integrity, including wound …

Abstract (163 words) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
induces coronavirus-19 disease (COVID-19) and is a major health concern. Following two …

Immune dysregulation is characteristic of the more severe stages of SARS-CoV-2 infection.
Understanding the mechanisms by which the immune system contributes to COVID-19 …

Vascular injury has emerged as a complication contributing to morbidity in coronavirus
disease 2019 (COVID-19). The glycosaminoglycan hyaluronan (HA) is a major component …

Background Limited clinical data suggest a~ 16% prevalence of bacterial superinfections
among critically ill patients with coronavirus disease 2019 (COVID-19). Methods We …

SARS-CoV-2 vaccinations have greatly reduced COVID-19 cases, but we must continue to
develop our understanding of the nature of the disease and its effects on human immunity …

Invasive mould disease (IMD) might affect up to a third of critically ill patients with COVID-19.
COVID-19-associated pulmonary aspergillosis (CAPA) is typically diagnosed on the basis of …