A comprehensive review on fused heterocyclic as DNA intercalators: Promising anticancer agents

V Sharma, M Gupta, P Kumar… - Current Pharmaceutical …, 2021 - ingentaconnect.com
Since the discovery of DNA intercalating agents (by Lerman, 1961), a growing number of
organic, inorganic, and metallic compounds have been developed to treat life-threatening …

Intercalation of Organic Dye Molecules into Double‐stranded DNA. Part 2: The Annelated Quinolizinium Ion as a Structural Motif in DNA Intercalators

H Ihmels, K Faulhaber, D Vedaldi… - Photochemistry and …, 2005 - Wiley Online Library
ABSTRACT DNA intercalators represent an important class of compounds with a high
potential as DNA‐targeting drugs. In this review it is demonstrated that annelated …

Novel Cyano- and Amidino-Substituted Derivatives of Styryl-2-Benzimidazoles and Benzimidazo[1,2-a]quinolines. Synthesis, Photochemical Synthesis, DNA Binding …

M Hranjec, M Kralj, I Piantanida, M Sedić… - Journal of medicinal …, 2007 - ACS Publications
Synthesis of novel cyano-and amidino-substituted styryl-2-benzimidazoles and benzimidazo
[1, 2-a] quinolines by condensation reactions and photochemical dehydrocyclization and …

Yttrium‐Catalyzed Addition of Benzylic C H Bonds of Alkyl Pyridines to Olefins

BT Guan, B Wang, M Nishiura… - Angewandte Chemie …, 2013 - Wiley Online Library
It is well-known that the benzylic CÀH bonds of α-alkyl pyridines react with electrophiles to
form CÀC bonds in a nucleophilic fashion.[1–6] However, the substrate scope reported so …

Ruthenium-catalyzed oxidation of alkenes at room temperature: a practical and concise approach to α-diketones

S Chen, Z Liu, E Shi, L Chen, W Wei, H Li… - Organic …, 2011 - ACS Publications
The catalytic oxidation of alkenes to α-diketones is unprecedented. A new oxidation of
alkenes, catalyzed by a ruthenium complex, which allows an efficient route to α-diketones …

Benzimidazole derivatives related to 2, 3-acrylonitriles, benzimidazo [1, 2-a] quinolines and fluorenes: synthesis, antitumor evaluation in vitro and crystal structure …

M Hranjec, G Pavlović, M Marjanović, M Kralj… - European journal of …, 2010 - Elsevier
A synthesis and biological evaluation of new benzimidazole derivatives, related to 2, 3-
disubstituted acrylonitriles, benzimidazo [1, 2-a] quinoline-6-carbonitriles and …

Preparation, Use, and Safety of O-Mesitylenesulfonylhydroxylamine

J Mendiola, JA Rincón, C Mateos… - … process research & …, 2009 - ACS Publications
The aminating reagent O-mesitylsulfonylhydroxylamine (MSH) has a known potential hazard
since it contains high-energy functional groups in its structure. There are references in the …

Regioselective Benzylic C–H Alumination and Further Functionalization of 2-Alkylpyridines by Yttrium Catalyst

M Takimoto, M Liu, M Nishiura, Z Hou - ACS Catalysis, 2022 - ACS Publications
The regioselective benzylic C–H alumination of various symmetrical and nonsymmetrical 2,
6-alkylpyridines catalyzed by a half-sandwich yttrium complex has been developed. The …

An environmentally benign cascade reaction of chromone-3-carboxaldehydes with ethyl 2-(pyridine-2-yl) acetate derivatives for highly site-selective synthesis of …

L Chen, R Huang, K Li, XH Yun, CL Yang, SJ Yan - Green Chemistry, 2020 - pubs.rsc.org
A novel protocol for the synthesis of quinolizines (3) and quinolizinium salts (4) from
chromone-3-carboxaldehydes 1 with ethyl 2-(pyridine-2-yl) acetate derivatives 2via an …

Synthesis and biological evaluation of imidazo [2, 1-b] thiazole-benzimidazole conjugates as microtubule-targeting agents

MF Baig, VL Nayak, P Budaganaboyina, K Mullagiri… - Bioorganic …, 2018 - Elsevier
Abstract A series of imidazo [2, 1-b] thiazole-benzimidazole conjugates were synthesized
and evaluated for their antiproliferative activity against four human cancer cell lines ie; HeLa …