p38MAPK signaling pathway in osteoarthritis: pathological and therapeutic aspects
Z Li, A Dai, M Yang, S Chen, Z Deng… - Journal of inflammation …, 2022 - Taylor & Francis
Osteoarthritis (OA) is an aging-related joint disease, pathologically featured with
degenerated articular cartilage and deformation of subchondral bone. OA has become the …
degenerated articular cartilage and deformation of subchondral bone. OA has become the …
Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup
FX Guix, AM Capitán… - Life science …, 2021 - life-science-alliance.org
As neurons age, they show a decrease in their ability to degrade proteins and membranes.
Because undegraded material is a source of toxic products, defects in degradation are …
Because undegraded material is a source of toxic products, defects in degradation are …
DUSP2 affects bladder cancer prognosis by down-regulating MEK/ERK and P38 MAPK signaling pathways through PTPN7
F Zou, T Rao, W Chen, T Song, T Li, W Hu, L Li, W Yu… - Cellular …, 2023 - Elsevier
Background As one of the leading causes of cancer death worldwide, bladder cancer (BCa)
ranks 12th in incidence rate. Dual Specific Phosphatase 2 (DUSP2) is a member of the …
ranks 12th in incidence rate. Dual Specific Phosphatase 2 (DUSP2) is a member of the …
Investigating the Multitarget Mechanism of Traditional Chinese Medicine Prescription for Cancer‐Related Pain by Using Network Pharmacology and Molecular …
J Chang, L Liu, Y Wang, Y Sui, H Li… - Evidence‐Based …, 2020 - Wiley Online Library
Gu‐tong formula (GTF) has achieved good curative effects in the treatment of cancer‐related
pain. However, its potential mechanisms have not been explored. We used network …
pain. However, its potential mechanisms have not been explored. We used network …
DNA methylation signatures in the prefrontal cortex of alcohol-naïve nonhuman primates predict risk for future ethanol drinking.
RC Juanes, K Zimmerman, L Wilhelm, C Lowe… - 2024 - researchsquare.com
Alcohol use disorder (AUD) is a highly prevalent, complex, multifactorial and heterogeneous
disorder, with 11% and 30% of adults meeting criteria for past-year and lifetime AUD …
disorder, with 11% and 30% of adults meeting criteria for past-year and lifetime AUD …
Biological mechanisms underlying susceptibility to traumatic stress: evidence from rodent models
A Ning - 2024 - cris.maastrichtuniversity.nl
Mental health and neurodegenerative disorders pose enormous personal and
socioeconomic burdens worldwide. Among the mental disorders, schizophrenia and bipolar …
socioeconomic burdens worldwide. Among the mental disorders, schizophrenia and bipolar …