Neuromodulation in epilepsy: state-of-the-art approved therapies

P Ryvlin, S Rheims, LJ Hirsch, A Sokolov… - The Lancet …, 2021 - thelancet.com
Three neuromodulation therapies have been appropriately tested and approved in refractory
focal epilepsies: vagus nerve stimulation (VNS), deep brain stimulation of the anterior …

Psychiatric face of COVID-19

L Steardo Jr, L Steardo, A Verkhratsky - Translational psychiatry, 2020 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) represents a severe multiorgan
pathology which, besides cardio-respiratory manifestations, affects the function of the central …

Efficacy and safety of fenfluramine for the treatment of seizures associated with Lennox-Gastaut syndrome: a randomized clinical trial

KG Knupp, IE Scheffer, B Ceulemans… - JAMA …, 2022 - jamanetwork.com
Importance New treatment options are needed for patients with Lennox-Gastaut syndrome
(LGS), a profoundly impairing, treatment-resistant, developmental and epileptic …

Automated seizure detection using wearable devices: a clinical practice guideline of the International League Against Epilepsy and the International Federation of …

S Beniczky, S Wiebe, J Jeppesen, WO Tatum… - Clinical …, 2021 - Elsevier
The objective of this clinical practice guideline (CPG) is to provide recommendations for
healthcare personnel working with patients with epilepsy, on the use of wearable devices for …

Machine learning and wearable devices of the future

S Beniczky, P Karoly, E Nurse, P Ryvlin, M Cook - Epilepsia, 2021 - Wiley Online Library
Abstract Machine learning (ML) is increasingly recognized as a useful tool in healthcare
applications, including epilepsy. One of the most important applications of ML in epilepsy is …

Autonomic manifestations of epilepsy: emerging pathways to sudden death?

RD Thijs, P Ryvlin, R Surges - Nature Reviews Neurology, 2021 - nature.com
Epileptic networks are intimately connected with the autonomic nervous system, as
exemplified by a plethora of ictal (during a seizure) autonomic manifestations, including …

Epilepsy and COVID-19: associations and important considerations

N Kuroda - Epilepsy & Behavior, 2020 - Elsevier
Coronavirus disease 2019 (COVID-19) is a novel infectious disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), and the outbreak, which initially …

Adjunctive cenobamate in highly active and ultra‐refractory focal epilepsy: a “real‐world” retrospective study

J Peña‐Ceballos, PB Moloney, T Munteanu… - …, 2023 - Wiley Online Library
Objective Recent clinical trials have shown that cenobamate substantially improves seizure
control in focal‐onset drug‐resistant epilepsy (DRE). However, little is known about …

[HTML][HTML] Impact of fenfluramine on the expected SUDEP mortality rates in patients with Dravet syndrome

JH Cross, BS Galer, A Gil-Nagel, O Devinsky… - Seizure, 2021 - Elsevier
Purpose To assess the impact of fenfluramine (FFA) on the expected mortality incidence,
including sudden unexpected death in epilepsy (SUDEP), in persons with Dravet syndrome …

Wearable digital health technology for epilepsy

E Donner, O Devinsky, D Friedman - New England Journal of …, 2024 - Mass Medical Soc
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