Advances in the treatment of gastroenteropancreatic neuroendocrine carcinomas: are we moving forward?

R Garcia-Carbonero, B Anton-Pascual… - Endocrine …, 2023 - academic.oup.com
Poorly differentiated gastroenteropancreatic neuroendocrine carcinomas are aggressive
neoplasms of challenging clinical management. A small proportion of patients with early …

Potent molecular-targeted therapies for gastro-entero-pancreatic neuroendocrine carcinoma

A Ooki, H Osumi, K Fukuda, K Yamaguchi - Cancer and Metastasis …, 2023 - Springer
Neuroendocrine neoplasms (NENs), which are characterized by neuroendocrine
differentiation, can arise in various organs. NENs have been divided into well-differentiated …

European Neuroendocrine Tumor Society (ENETS) 2023 guidance paper for digestive neuroendocrine carcinoma

H Sorbye, E Grande, M Pavel… - Journal of …, 2023 - Wiley Online Library
This ENETS guidance paper, developed by a multidisciplinary working group, provides up‐
to‐date and practical advice on the diagnosis and management of digestive neuroendocrine …

Bevacizumab plus FOLFIRI after failure of platinum–etoposide first-line chemotherapy in patients with advanced neuroendocrine carcinoma (PRODIGE 41-BEVANEC) …

T Walter, A Lievre, R Coriat, D Malka, F Elhajbi… - The Lancet …, 2023 - thelancet.com
Background There is no standard second-line treatment after platinum–etoposide
chemotherapy for gastroenteropancreatic neuroendocrine carcinoma. We aimed to evaluate …

Chemotherapy in well differentiated neuroendocrine tumors (NET) G1, G2, and G3: a narrative review

A Zappi, I Persano, L Galvani, E Parlagreco… - Journal of Clinical …, 2023 - mdpi.com
Neuroendocrine tumors (NETs) are rare neoplasms with a wide spectrum of clinical
behavior, from the long survival of well-differentiated NETs to the dismal prognosis of high …

[HTML][HTML] Progress in immunotherapy for neuroendocrine neoplasm of the digestive system

WX Pan, XM Zhang, SL Hao, W Han - World Journal of …, 2023 - ncbi.nlm.nih.gov
Neuroendocrine neoplasms (NENs) are rare heterogeneous tumors that can develop in
almost any organ, with the digestive organs, including the gastrointestinal tract and …

Immunotherapy for endocrine tumours: A clinician's perspective

A Angelousi, P Tzoulis, M Tsoli… - Endocrine-Related …, 2024 - erc.bioscientifica.com
Immunotherapy has revolutionised the treatment of oncological patients, but its application
in various endocrine tumours is rather limited and is mainly used when conventional …

A systematic review of therapeutic strategies in gastroenteropancreatic grade 3 neuroendocrine tumors

MD Donadio, ÂB Brito… - … Advances in Medical …, 2023 - journals.sagepub.com
Background: Gastroenteropancreatic (GEP) neuroendocrine neoplasms with Ki-67> 20%
were subdivided in the most recent 2019 World Health Organization histopathological …

[HTML][HTML] Immunotherapy in neuroendocrine neoplasms: a diamond to cut

E García-Torralba, E Garcia-Lorenzo, B Doger… - Cancers, 2024 - mdpi.com
Simple Summary The development of new treatments for patients with neuroendocrine
neoplasms (NENs) is imperative. Immunotherapy has shown efficacy in various neoplasms …

SEOM-GETNE clinical guidelines for the diagnosis and treatment of gastroenteropancreatic and bronchial neuroendocrine neoplasms (NENs)(2022)

JC Castillón, TA Gordoa, AC Bayonas… - Clinical and …, 2023 - Springer
Neuroendocrine neoplasms (NENs) are a heterogeneous family of tumors of challenging
diagnosis and clinical management. Their incidence and prevalence continue to rise mainly …