Asymmetric phosphine catalysis showcasing remarkable progress over the past two
decades has emerged as a key synthetic platform for the creation of molecular frameworks …

Methods to functionalize arenes and heteroarenes in a site-selective manner are highly
sought after for rapidly constructing value-added molecules of medicinal, agrochemical, and …

Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

The fundamental role of the Lewis-acid catalyst lies in the activation of the CdX bond (X) O,
NR, CR2), thereby decreasing the LUMO energy and promoting nucleophilic addition to the …

Organic synthesis is one of the most successful and useful disciplines of science and mainly
involves the construction of carbon-carbon bond (s) and carbon-heteroatom bond (s) and …

Catalytic asymmetric synthesis has received considerable attention over the past few
decades, becoming a highly dynamic area of chemical research with significant …

The utilization of hydrogen bonding as an activation force has become a powerful tool in
asymmetric organocatalysis. Significant advances have been made in the recent past in this …

Tethering a metal complex to its phosphate counterion via a phosphine ligand enables a
new strategy in asymmetric counteranion-directed catalysis (ACDC). A straightforward …

The broad potential synthetic usefulness of phosphine-promoted reactions has stimulated
many recent investigations on enantioselective variants of known reactions of this family, as …

Catalytic asymmetric [3+ 2]-cycloaddition reactions between α-allenic esters and enones are
presented. We have found that a simple phosphine-containing protected α-amino acid …