[HTML][HTML] Omics Science and Social Aspects in Detecting Biomarkers for Diagnosis, Risk Prediction, and Outcomes of Carotid Stenosis

D Costa, E Scalise, N Ielapi, UM Bracale… - …, 2024 - pmc.ncbi.nlm.nih.gov
Carotid stenosis is characterized by the progressive narrowing of the carotid arteries due to
the formation of atherosclerotic plaque, which can lead to stroke and death as major …

Spatial transcriptomic mapping of coronary atherosclerosis in the luminal plaque and beyond

P Cheng, T Quertermous - Nature Cardiovascular Research, 2025 - nature.com
Single-cell transcriptomic studies have primarily focused on cell-autonomous mechanisms
in coronary atherosclerosis. A study mapping the spatial transcriptome of cells in the …

Epigenetic Remodeling in Human Coronary Artery Smooth Muscle Cell Phenotypic Switching

R Chakraborty, VP Schulz, K Lezon-Geyda, JM Dave… - bioRxiv, 2024 - biorxiv.org
Background: Smooth muscle cell (SMC) dedifferentiation contributes to repair and
remodeling, but also cardiovascular pathologies. To understand this plasticity, the …