Diabetes (type 2) and sensorineural hearing loss are common health problems manifested
with ageing. While both type 1 and type 2 diabetes have been associated with hearing loss …

The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …

Purpose There is still a clinical-radiologic discrepancy in patients with Menière's disease
(MD). Therefore, the purpose of this study was to investigate the reliability of current MRI …

Diverse specialised neuroglial cells guarantee the development, preservation, and health of
the central nervous system, the peripheral nervous system, the enteric nervous system, and …

The isolated anatomical position and blood-labyrinth barrier hampers systemic drug delivery
to the mammalian inner ear. Intratympanic placement of drugs and permeation via the round …

Cisplatin is a widely used anticancer drug with notable side effects including ototoxicity and
nephrotoxicity. Macrophages, the major resident immune cells in the cochlea and kidney …

Significance: The stria vascularis, located in the inner ear, consists of three layers, one of
which is the blood–labyrinth barrier (BLB). It is formed by endothelial cells, sealed together …

The relationship between Menière's disease and endolymphatic hydrops is ambiguous. On
the one hand, the existence of cases of endolymphatic hydrops lacking the classic …

Hearing loss is one of the 10 leading causes of disability worldwide. No drug therapies are
currently available to protect or restore hearing. Inner ear auditory hair cells and the blood …

It has been challenging to apply intravital imaging for monitoring the inner ear, as the
anatomical location and intricate structure hamper the access of imaging instruments to the …