Simple Summary Cellular proliferation is a central determinant of breast cancer recurrence
risk and response to chemotherapy. The discovery of the Ki-67 antibody by Dr. Johannes …

PURPOSE To update key recommendations of the American Society of Clinical
Oncology/College of American Pathologists estrogen (ER) and progesterone receptor (PgR) …

Purpose.—To update key recommendations of the American Society of Clinical
Oncology/College of American Pathologists estrogen receptor (ER) and progesterone …

Background Proliferation may predict response to neoadjuvant therapy of breast cancer and
is commonly assessed by manual scoring of slides stained by immunohistochemistry (IHC) …

Introduction and objectives Checkpoint inhibition has emerged as new therapeutic option in
muscle-invasive bladder cancer. The objective of the present study was to evaluate the …

Background Chemokines, cytokines in the immune microenvironment of tumors, may be
associated with patient outcome. We assessed the impact of CXCL13 and CXCL9 on …

This viewpoint is a personal reflection on the values and merits of immunohistochemistry in
current breast cancer diagnosis. Immunohistochemistry is a validated mainstay in molecular …

Transcriptional profiling is a powerful tool to investigate and detect human diseases. In this
study, we used bulk RNA-sequencing (RNA-Seq) to compare the transcriptomes in skin …

Background Accurate determination of the predictive markers human epidermal growth
factor receptor 2 (HER2/ERBB2), estrogen receptor (ER/ESR1), progesterone receptor …

Simple Summary We examined the relevance of immunoglobulin kappa C (IGKC), an
important part of the humoral immune system, in early breast cancer. To our knowledge, our …