[HTML][HTML] Phytochemicals for human disease: An update on plant-derived compounds antibacterial activity

R Barbieri, E Coppo, A Marchese, M Daglia… - Microbiological …, 2017 - Elsevier
In recent years, many studies have shown that phytochemicals exert their antibacterial
activity through different mechanisms of action, such as damage to the bacterial membrane …

Antioxidant, Anti-Inflammatory and Cytotoxic Activity of Phenolic Compound Family Extracted from Raspberries (Rubus idaeus): A General Review

AV Lopez-Corona, I Valencia-Espinosa… - Antioxidants, 2022 - mdpi.com
Raspberries (Rubus idaeus) possess a wide phenolic family profile; this serves the role of
self-protection for the plant. Interest in these compounds have significantly increased, since …

Urolithins, the rescue of “old” metabolites to understand a “new” concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health …

FA Tomás‐Barberán… - Molecular nutrition & …, 2017 - Wiley Online Library
Urolithins are dibenzo [b, d] pyran‐6‐one derivatives that are produced by the human gut
microbiota from ellagitannins and ellagic acid (EA). These metabolites are much better …

Understanding the molecular mechanisms of the interplay between herbal medicines and gut microbiota

J Xu, HB Chen, SL Li - Medicinal Research Reviews, 2017 - Wiley Online Library
Herbal medicines (HMs) are much appreciated for their significant contribution to human
survival and reproduction by remedial and prophylactic management of diseases. Defining …

An overview on dietary polyphenols and their biopharmaceutical classification system (BCS)

F Truzzi, C Tibaldi, Y Zhang, G Dinelli… - International Journal of …, 2021 - mdpi.com
Polyphenols are natural organic compounds produced by plants, acting as antioxidants by
reacting with ROS. These compounds are widely consumed in daily diet and many studies …

Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis

HJ Lee, YH Jung, GE Choi, JS Kim, CW Chae… - Cell Death & …, 2021 - nature.com
Hyperglycemia in diabetes mellitus (DM) patients is a causative factor for amyloidogenesis
and induces neuropathological changes, such as impaired neuronal integrity …

Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection

WR García-Niño, C Zazueta - Pharmacological Research, 2015 - Elsevier
Traditional drugs or therapies rarely have effects on regression of chronic liver diseases,
which result in many cases from sustained oxidative stress. In recent years, ellagic acid (EA) …

Metabolic and microbial modulation of the large intestine ecosystem by non-absorbed diet phenolic compounds: A review

JI Mosele, A Macià, MJ Motilva - Molecules, 2015 - mdpi.com
Phenolic compounds represent a diverse group of phytochemicals whose intake is
associated with a wide spectrum of health benefits. As consequence of their low …

Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice

B Xia, XC Shi, BC Xie, MQ Zhu, Y Chen, XY Chu… - PLoS …, 2020 - journals.plos.org
Obesity leads to multiple health problems, including diabetes, fatty liver, and even cancer.
Here, we report that urolithin A (UA), a gut-microflora–derived metabolite of pomegranate …

Gastrointestinal interactions, absorption, splanchnic metabolism and pharmacokinetics of orally ingested phenolic compounds

JA Domínguez-Avila, A Wall-Medrano… - Food & Function, 2017 - pubs.rsc.org
The positive health effects of phenolic compounds (PCs) have been extensively reported in
the literature. An understanding of their bioaccessibility and bioavailability is essential for the …