Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

Protein lipidation is an important co-or posttranslational modification in which lipid moieties
are covalently attached to proteins. Lipidation markedly increases the hydrophobicity of …

Hypoxia is one of the most common and severe challenges to the maintenance of
homeostasis. Oxygen sensing is a property of all tissues, and the response to hypoxia is …

The lipid post‐translational modification S‐palmitoylation is a vast developing field, with the
modification itself and the enzymes that catalyse the reversible reaction implicated in a …

Protein palmitoylation, in which C16 fatty acid chains are attached to cysteine residues via a
reversible thioester linkage, is one of the most common lipid modifications and plays …

The microvascular endothelium serves as the major barrier that controls the transport of
blood constituents across the vessel wall. Barrier leakage occurs during infection or sterile …

Extracellular vesicles (EVs) have attracted rising interests in the cardiovascular field not only
because they serve as serological markers for circulatory disorders but also because they …

Atherosclerosis is the underlying cause for cardiovascular disease. Current
pharmacotherapies are limited by the inadequate targeting and insufficient treatment …

S-acylation is a reversible protein post-translational modification mediated by protein S-
acyltransferases (PATs). How S-acylation regulates plant innate immunity is our main …

S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about
the DHHC palmitoyltransferase family is still limited. Here we show that human ZDHHC6 …