Genetic versus self-reported African ancestry of the recipient and neighborhood predictors of kidney transplantation outcomes in 2 multiethnic urban cohorts

F Zanoni, YD Neugut, JE Obayemi, L Liu… - American Journal of …, 2024 - Elsevier
African American (AA) kidney recipients have a higher risk of allograft rejection and failure
compared to non-AAs, but to what extent these outcomes are due to genetic versus …

[图书][B] Therapeutic drug monitoring: newer drugs and biomarkers

A Dasgupta - 2024 - books.google.com
Therapeutic Drug Monitoring 2nd Edition is an updated reference on TDM analytical
techniques in diverse clinical settings. This new edition reviews the exciting new …

Au/Ag@ ZIF-8 nanocomposite as solid phase extraction adsorbent and SERS substrate for tacrolimus label-free therapeutic drug monitoring in human serum

Y Zhan, J Cao, Y Wang, X Li, Y Li, H Zeng, W Huang… - Talanta, 2025 - Elsevier
Abstract Surface Enhanced Raman Scattering (SERS) has been extensively utilized in
therapeutic drug monitoring (TDM) due to its rapid detection speed, high sensitivity and …

Quantitatively measuring the cytotoxicity of viscous hydrogels with direct cell sampling in a micro scale format “MicroDrop” and its comparison to CCK8

AM Margot, A Engels, M Sittinger, T Dehne… - Journal of Materials …, 2024 - Springer
Tissue engineering holds promise for developing therapeutic applications using viscous
materials eg hydrogels. However, assessing the cytotoxicity of such materials with …

Consequences of differences in bio-analytical assays for the precision monitoring of immunosuppressive drugs

S Cremers, A Lyashchenko - Therapeutic Drug Monitoring, 2024 - Elsevier
Immunosuppressant therapy requires routine therapeutic drug monitoring. Cyclosporine,
tacrolimus, sirolimus, and everolimus are monitored in whole blood, while another …

Immunosuppressant Monitoring—Performance of the First Mass Spectrometry–Based Automated Clinical Analyzer Cascadion

D Grote-Koska, S Czajkowski, A Staaden… - Therapeutic Drug …, 2023 - journals.lww.com
Background: Automatic analyzers simplify processes and may help improve standardization.
The first automated analyzer based on mass spectrometry is available and offers a panel for …

Multicenter Prospective Trial Evaluating the Utility of CYP3A5 Genotype in Determining Optimal Initial Dosage of Tacrolimus in Chinese Renal Transplant Recipients

X Zhang, W Tong, H Chen, S Fu, N Lei, G Li, Z Zhang… - 2023 - researchsquare.com
Purpose Tacrolimus is a potent immunosuppressant extensively, due to different gene
expressions of CYP3A5 in different populations, tacrolimus has a narrow therapeutic index …