Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents

FJ Chen, MV Patel - US Patent 6,383,471, 2002 - Google Patents
BACKGROUND Hydrophobic therapeutic agents, ie, therapeutic com pounds having poor
Solubility in aqueous Solution, present difficult problems in formulating Such compounds for …

Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents

MV Patel, FJ Chen - US Patent 6,294,192, 2001 - Google Patents
The present invention relates to triglyceride-free pharmaceutical compositions for delivery of
hydrophobic therapeutic agents. Compositions of the present invention include a …

Compositions and methods for improved delivery of hydrophobic agents

MV Patel, FJ Chen - US Patent 6,451,339, 2002 - Google Patents
The present invention relates to triglyceride-free pharmaceutical compositions for delivery of
hydrophobic therapeutic agents. Compositions of the present invention include a …

Emulsion compositions for polyfunctional active ingredients

FJ Chen, MV Patel - US Patent 6,720,001, 2004 - Google Patents
The present invention provides pharmaceutical oil-in-water emulsions for delivery of
polyfunctional active ingredients. The emulsions include an aqueous phase, an emulsifier …

Clear oil-containing pharmaceutical compositions

FJ Chen, MV Patel - US Patent 6,267,985, 2001 - Google Patents
BACKGROUND A Wide variety of therapeutic agents, such as drugs, nutritional agents, and
cosmeceuticals, are conventionally formulated in oil/Water emulsion systems. These conven …

Therapeutic inhibitor of vascular smooth muscle cells

LL Kunz, RA Klein, JM Reno, DJ Grainger… - US Patent …, 1998 - Google Patents
Methods are provided for inhibiting stenosis following vas cular trauma or disease in a
mammalian host, comprising administering to the host a therapeutically effective dosage of a …

Clear oil-containing pharmaceutical compositions containing a therapeutic agent

FJ Chen, MV Patel, DT Fikstad - US Patent 6,761,903, 2004 - Google Patents
The present invention relates to pharmaceutical compositions and methods for improved
solubilization of triglycerides and improved delivery of therapeutic agents. Compositions of …

Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents

MV Patel, FJ Chen - US Patent 6,309,663, 2001 - Google Patents
The present invention relates to pharmaceutical compositions, pharmaceutical systems, and
methods for enhanced absorption of hydrophilic therapeutic agents. Compositions and …

Therapeutic inhibitor of vascular smooth muscle cells

LL Kunz, RA Klein, JM Reno - US Patent 5,981,568, 1999 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
33479843&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Pharmaceutical compositions containing an omega-3 fatty acid oil

A Mishra, I Moussa, Z Ramtoola, N Clarke - US Patent 6,284,268, 2001 - Google Patents
Self-emulsifying microemulsion or emulsion preconcentrate pharmaceutical compositions
containing an omega-3 fatty acid oil Such as a fish oil and a poorly water Soluble …