[HTML][HTML] Pathology and pathogenesis of human leptospirosis: a commented review

T De Brito, AMG Silva, PAE Abreu - Revista do Instituto de Medicina …, 2018 - SciELO Brasil
Leptospirosis is an acute bacterial septicemic febrile disease caused by pathogenic
leptospires, which affect humans and animals in all parts of the world. Transmission can …

Pigment nephropathy: novel insights into inflammasome-mediated pathogenesis

KTK Giuliani, AJ Kassianos, H Healy… - International Journal of …, 2019 - mdpi.com
Pigment nephropathy is an acute decline in renal function following the deposition of
endogenous haem-containing proteins in the kidneys. Haem pigments such as myoglobin …

Pathology and host immune evasion during human leptospirosis: a review

VK Chin, R Basir, SA Nordin, M Abdullah… - International …, 2020 - Springer
Human leptospirosis is considered as one of the most widespread and potentially fatal
zoonotic diseases that causes high mortality and morbidity in the endemic regions of tropical …

Non-purulent myositis caused by direct invasion of skeletal muscle tissue by Leptospira in a hamster model

S Miyahara, H Mori, K Fukuda, M Ogawa… - Infection and …, 2024 - Am Soc Microbiol
Myalgia is a common symptom of Leptospira infection in humans. Autopsies have reported
that muscle tissue shows degeneration and necrosis of the myofibers and infiltration of …

Role of Supramolecule ErpY-Like Lipoprotein of Leptospira in Thrombin-Catalyzed Fibrin Clot Inhibition and Binding to Complement Factors H and I, and Its …

KK Ghosh, A Prakash, A Dhara, MS Hussain… - Infection and …, 2019 - Am Soc Microbiol
Leptospirosis is one of the most widespread zoonoses caused by pathogenic Leptospira
spp. In this study, we report that the LIC11966/ErpY-like lipoprotein is a surface-exposed …

An historical view of the experimental leptospiral infection in ruminants

BR Rocha, G Martins, W Lilenbaum - … Immunology, Microbiology and …, 2020 - Elsevier
The first experimental infections with Leptospira in ruminants were conducted in the 1950s,
primarily assessed the pathogenesis caused by serovar Pomona in cows. Throughout the …

[HTML][HTML] Detection of Leptospira in urine of apparently healthy dogs by quantitative polymerase chain reaction in Haryana, India

P Rohilla, R Khurana, A Kumar, K Batra… - Veterinary …, 2020 - ncbi.nlm.nih.gov
Materials and Methods: Leptospirosis is a zoonotic disease caused by bacteria of the genus
Leptospira. To detect the pathogenic Leptospira organisms in dogs' urinary shedding, 239 …

Evaluation of a novel outer membrane surface-exposed protein, LIC13341 of Leptospira, as an adhesin and serodiagnostic candidate marker for leptospirosis

KK Ghosh, A Prakash, P Shrivastav… - …, 2018 - microbiologyresearch.org
The outer membrane proteins of the pathogen are targeted to understand host–pathogen
interactions and are central to the development of diagnostics. We report that Leptospira …

Acute Kidney Injury Associated with Severe Leptospirosis: Fatal Re-Emerging Disease in Latin America

E Osorio-Rodríguez, D Rodelo-Barrios… - Kidney and …, 2024 - mdpi.com
Leptospirosis is a re-emerging zoonotic disease that has had an unprecedented impact on
most health systems in the world. The spectrum of symptoms is variable and usually ranges …

Role of Murine Complement Component C5 in Acute in Vivo Infection by Pathogenic Leptospira interrogans

IRA De Castro, L Bavia, TR Fraga… - Frontiers in Cellular …, 2018 - frontiersin.org
Leptospirosis is considered one of the most important zoonosis worldwide. The activation of
the Complement System is important to control dissemination of several pathogens in the …