Any opinions, findings, and conclusions or recommendations expressed in this material are
those of the authors and do not necessarily reflect the views of the US Army Contracting …

Hyponatremia is a serious, but often overlooked, electrolyte imbalance that has been
independently associated with a wide range of deleterious changes involving many different …

Background Acute treatment of cerebral edema and elevated intracranial pressure is a
common issue in patients with neurological injury. Practical recommendations regarding …

Background and Purpose—The authors present an overview of the current evidence and
management recommendations for evaluation and treatment of adults with acute ischemic …

Pediatric acute liver failure (PALF) is a rare, rapidly progressive clinical syndrome with
significant morbidity and mortality. The phenotype of PALF manifests as abrupt onset liver …

Intracerebral haemorrhage (ICH) is the most devastating and disabling type of stroke.
Uncontrolled hypertension (HTN) is the most common cause of spontaneous ICH. Recent …

Objectives: Randomized trials have suggested that hypertonic saline solutions may be
superior to mannitol for the treatment of elevated intracranial pressure, but their impact on …

Hyponatremia is the most common electrolyte disorder, affecting more than 15% of patients
in the hospital. Syndrome of inappropriate antidiuresis (SIAD) is the most frequent cause of …

Patients with severe (serum sodium≤ 120 mEq/L), symptomatic hyponatremia can develop
life-threatening or fatal complications from cerebral edema if treatment is inadequate and …

Acute liver failure (ALF) is a dynamic clinical condition manifested by an abrupt onset of a
liver-based coagulopathy and biochemical evidence of hepatocellular injury resulting from …