Many cognitive abilities decline with age even in the absence of detectable pathology.
Recent evidence indicates that age-related neural dedifferentiation, operationalized in terms …

As it was established that aging is not associated with massive neuronal loss, as was
believed in the mid‐20th Century, scientific interest has addressed the influence of aging on …

γ-Aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the human brain
and can be measured with magnetic resonance spectroscopy (MRS). Conflicting accounts …

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain.
Although measurements of GABA levels in vivo in the human brain using edited proton …

Neuronal homeostasis prevents hyperactivity and hypoactivity. Age-related hyperactivity
suggests homeostasis may be dysregulated in later life. However, plasticity mechanisms …

Aging is typically associated with declines in sensorimotor performance. Previous studies
have linked some age-related behavioral declines to reductions in network segregation. For …

This review focuses on possible contributions of neural dedifferentiation to age-related
cognitive decline. Neural dedifferentiation is held to reflect a breakdown in the functional …

Brain stimulation approaches are important to gain causal mechanistic insights into the
relevance of functional brain regions and/or neurophysiological systems for human cognitive …

Aging is accompanied by the deterioration of hearing that complicates our understanding of
speech, especially in noisy environments. This deficit is partially caused by the loss of hair …

In younger adults, arousal amplifies attentional focus to the most salient or goal-relevant
information while suppressing other information. A computational model of how the locus …