Nucleic acid-based therapeutics for dermal wound healing

P Sharma, A Kumar, T Agarwal, AD Dey… - International Journal of …, 2022 - Elsevier
Non-healing wounds have long been the subject of scientific and clinical investigations.
Despite breakthroughs in understanding the biology of delayed wound healing, only limited …

Peptide-based nanoassemblies in gene therapy and diagnosis: paving the way for clinical application

S Tarvirdipour, X Huang, V Mihali, CA Schoenenberger… - Molecules, 2020 - mdpi.com
Nanotechnology approaches play an important role in developing novel and efficient
carriers for biomedical applications. Peptides are particularly appealing to generate such …

Advances in D-amino acids in neurological research

JM Seckler, SJ Lewis - International journal of molecular sciences, 2020 - mdpi.com
D-amino acids have been known to exist in the human brain for nearly 40 years, and they
continue to be a field of active study to today. This review article aims to give a concise …

Gene delivery nanoparticles to modulate angiogenesis

J Kim, AC Mirando, AS Popel, JJ Green - Advanced drug delivery reviews, 2017 - Elsevier
Angiogenesis is naturally balanced by many pro-and anti-angiogenic factors while an
imbalance of these factors leads to aberrant angiogenesis, which is closely associated with …

Nanosystems for drug delivery: Design, engineering, and applications

V Dhapte, V Pokharkar - Green Synthesis, Characterization and …, 2019 - Elsevier
The evolution of nanotechnology has initiated a revolution in the biomedical and
pharmaceutical fields. The nature of a nanocarrier and its payload has played a remarkable …

Peptides as key components in the design of non‐viral vectors for gene delivery

J Thomas, K Punia, JK Montclare - Peptide Science, 2021 - Wiley Online Library
Successful clinical implementation of gene delivery relies on the use of viral or non‐viral
based vectors to package and protect the therapeutic nucleic acid. These vehicles must also …

[HTML][HTML] Overcoming the challenge: cell-penetrating peptides and membrane permeability

Y Gu, L Wu, Y Hameed, M Nabi-Afjadi - Biomaterials and …, 2023 - anserpress.org
Cell-penetrating peptides (CPPs) have emerged as a promising strategy for enhancing the
membrane permeability of bioactive molecules, particularly in the treatment of central …

Cys-flanked cationic peptides for cell delivery of the herpes simplex virus thymidine kinase gene for suicide gene therapy of uterine leiomyoma

AA Egorova, SV Shtykalova, MA Maretina, AV Selyutin… - Molecular Biology, 2020 - Springer
Uterine leiomyoma (UL) is the most common benign tumor in women of reproductive age.
Gene therapy using suicidal genes appears to be a promising approach for UL treatment …

Biopolymeric materials used as nonviral vectors: a review

JA Santos, DB Liarte, AB Ribeiro, MS Rizzo, MP Costa… - Polysaccharides, 2021 - mdpi.com
Bacterial transformation and gene transfection can be understood as being the results of
introducing specific genetic material into cells, resulting in gene expression, and adding a …

[PDF][PDF] Cys-фланкированные катионные пептиды для доставки гена тимидинкиназы вируса простого герпеса в клетки с целью суицидной генной терапии …

АА Егорова, СВ Штыкалова… - Молекулярная …, 2020 - researchgate.net
Миома матки (ММ)‒наиболее часто встречающаяся доброкачественная опухоль у
женщин репродуктивного возраста. В качестве подхода к лечению ММ может быть …