† Potential for biomarker-based interventions† Development of biomarkers in phases†
Summary background: Although surgery is currently the treatment of choice for managing …

17β-Estradiol (E2) controls many aspects of human physiology, including development,
reproduction and homeostasis, through regulation of the transcriptional activity of its cognate …

В доступной форме в книге изложены основные события, произошедшие в
медицинской генетике и в молекулярной медицине после расшифровки генома …

Steroid hormones exert profound effects on cell growth, development, differentiation, and
homeostasis. Their effects are mediated through specific intracellular steroid receptors that …

Endometriosis refers to the growth of ectopic endometrial tissue outside the uterine cavity.
About 10–15% of female in reproductive age suffer from endometriosis. Several etiologies …

Introduction Endometriosis is defined as the presence of endometrial tissue outside the
uterine cavity. Materials and Methods The etiology of this multifactorial disease is still …

BACKGROUND Endometriosis is an estrogen-dependent gynecological disorder that affects
at least 10% of women of reproductive age. It may lead to infertility and non-specific …

While the incidence of endometriosis is up to 40–60% in women with severe
dysmenorrhea/chronic pelvic pain, patients with subfertility carries a risk up to 20–30%. In …

Endometriosis is an estrogen-dependent inflammatory gynecological disease. Increased
estrogen activity and progesterone resistance are the main hormonal substrate of this …

BACKGROUND Endometriosis has a strong genetic component, and numerous genetic
studies have been reported. METHODS We have systematically reviewed these studies and …