Progress in our understanding of several biological processes promises to broaden the
usefulness of Escherichia coli as a tool for gene expression. There is an expanding choice …

In a wide variety of organisms, synonymous codons are used with different frequencies, a
phenomenon known as codon bias. Population genetic studies have shown that …

The genetic code, which defines the amino acid sequence of a protein, also contains
information that influences the rate and efficiency of translation. Neither the mechanisms nor …

Triacylglycerol (TG) is a storage lipid which serves as an energy reservoir and a source of
signalling molecules and substrates for membrane biogenesis. TG is essential for many …

The genetic code uses 64 codons to represent the 20 standard amino acids and the
translation termination signal. Each codon is recognised by a subset of a cell's transfer …

The pathogenic potential of Fusobacterium nucleatum and its significance in the
development of periodontal diseases, as well as in infections in other organs, have gained …

Cellular efficiency in protein translation is an important fitness determinant in rapidly growing
organisms. It is widely believed that synonymous codons are translated with unequal …

Background Correlations between genome composition (in terms of GC content) and usage
of particular codons and amino acids have been widely reported, but poorly explained. We …

Transfer RNA (tRNA) gene content is a differentiating feature of genomes that contributes to
the efficiency of the translational apparatus, but the principles shaping tRNA gene copy …

Among bacteria, many species have synonymous codon usage patterns that have been
influenced by natural selection for those codons that are translated more accurately and/or …