Imaging insights into basal ganglia function, Parkinson's disease, and dystonia

AJ Stoessl, S Lehericy, AP Strafella - The Lancet, 2014 - thelancet.com
Recent advances in structural and functional imaging have greatly improved our ability to
assess normal functions of the basal ganglia, diagnose parkinsonian syndromes …

Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate

OC Andronesi, O Rapalino, E Gerstner… - The Journal of …, 2013 - Am Soc Clin Investig
The investigation of metabolic pathways disturbed in isocitrate dehydrogenase (IDH) mutant
tumors revealed that the hallmark metabolic alteration is the production of D-2 …

3D GABA imaging with real-time motion correction, shim update and reacquisition of adiabatic spiral MRSI

W Bogner, B Gagoski, AT Hess, H Bhat, MD Tisdall… - Neuroimage, 2014 - Elsevier
Gamma-aminobutyric acid (GABA) and glutamate (Glu) are the major neurotransmitters in
the brain. They are crucial for the functioning of healthy brain and their alteration is a major …

Targeted transcranial theta-burst stimulation alters fronto-insular network and prefrontal GABA

SJ Iwabuchi, F Raschke, DP Auer, PF Liddle… - Neuroimage, 2017 - Elsevier
Repetitive transcranial magnetic stimulation (rTMS) has been used worldwide to treat
depression. However, the exact physiological effects are not well understood …

Cystathionine as a marker for 1p/19q codeleted gliomas by in vivo magnetic resonance spectroscopy

F Branzoli, C Pontoizeau, L Tchara… - Neuro …, 2019 - academic.oup.com
Background Codeletion of chromosome arms 1p and 19q (1p/19q codeletion) highly
benefits diagnosis and prognosis in gliomas. In this study, we investigated the effect of …

GABAergic changes in the thalamocortical circuit in Parkinson's disease

AJM van Nuland, HEM den Ouden, H Zach… - Human Brain …, 2020 - Wiley Online Library
Parkinson's disease is characterized by bradykinesia, rigidity, and tremor. These symptoms
have been related to an increased gamma‐aminobutyric acid (GABA) ergic inhibitory drive …

Striatal GABA-MRS predicts response inhibition performance and its cortical electrophysiological correlates

C Quetscher, A Yildiz, S Dharmadhikari… - Brain Structure and …, 2015 - Springer
Response inhibition processes are important for performance monitoring and are mediated
via a network constituted by different cortical areas and basal ganglia nuclei. At the basal …

[HTML][HTML] Transcranial magnetic stimulation and magnetic resonance spectroscopy: Opportunities for a bimodal approach in human neuroscience

K Cuypers, A Marsman - Neuroimage, 2021 - Elsevier
Over the last decade, there has been an increasing number of studies combining
transcranial magnetic stimulation (TMS) and magnetic resonance spectroscopy (MRS). MRS …

Associations between sensory processing and electrophysiological and neurochemical measures in children with ASD: an EEG-MRS study

S Pierce, G Kadlaskar, DA Edmondson… - Journal of …, 2021 - Springer
Background Autism spectrum disorder (ASD) is associated with hyper-and/or hypo-
sensitivity to sensory input. Spontaneous alpha power, which plays an important role in …

[HTML][HTML] Total GABA level in human auditory cortex is associated with speech-in-noise understanding in older age

SGJ Dobri, B Ross - Neuroimage, 2021 - Elsevier
Abstract Speech-in-noise (SIN) understanding often becomes difficult for older adults
because of impaired hearing and aging-related changes in central auditory processing …