Both the innate and adaptive immune responses are dependent on the migration of
leukocytes across endothelial cells. The process of diapedesis, in which the leukocyte …

Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kD member of the
immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets …

CD99 is a heavily O-glycosylated 32-kD type I transmembrane protein that is expressed on
most hematopoietic cells. We show here that CD99 is expressed on endothelial cells and is …

Remote ischemic preconditioning (IPC) reduces tissue injury caused by ischemia-
reperfusion (IR) in distant organs. We tested the hypothesis that remote IPC (rIPC) modifies …

I nflammation is the response of vascularized tissue to damage. It is a complex response set
in motion in any tissue by virtually any injury due to any cause. It is an attempt to restore …

When exposed to chronic sublethal hypoxia the developing brain responds with increases in
permeability and angiogenesis. Vascular endothelial growth factor (VEGF) may mediate this …

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a cell adhesion and
signaling receptor that is expressed on hematopoietic and endothelial cells. PECAM-1 is …

Background. Cardiac preconditioning is thought to be involved in the observed decreased
coronary artery reocclusion rate in patients with angina preceding myocardial infarction. We …

Under a variety of (patho) physiological conditions, leukocytes will leave the bloodstream by
crossing the endothelial monolayer that lines the vessels and migrate into the underlying …

Acute inflammation is a common dangerous component of pathogenesis of many prevalent
conditions with high morbidity and mortality including sepsis, thrombosis, acute respiratory …