Universally fatal only 4 decades ago, the progress in the 3-stage palliation of hypoplastic left
heart syndrome and related single right ventricular lesions has drastically improved the …

As the cohort of survivors with the single-ventricle type of congenital heart disease grows, it
becomes increasingly evident that the state of chronically elevated venous pressure and …

Background: There are limited long-term, single-cohort, follow-up studies available about
patients after the Fontan operation. Objectives: This study sought to determine the long-term …

Background: In the SVR trial (Single Ventricle Reconstruction), 1-year transplant-free
survival was better for the Norwood procedure with right ventricle-to-pulmonary artery shunt …

Background Congestive hepatopathy is a recognized complication of Fontan physiology.
Data regarding the incidence of hepatopathy and risk factors are lacking. Methods and …

Objective Existing studies of patients palliated with the Fontan operation are limited by
heterogeneous patient populations and incomplete follow-up. This study aimed to describe …

The Fontan operation is the anticipated palliative strategy for children born with single-
ventricle type of congenital heart disease. As a result of important circulatory limitations, a …

Rationale: Hypoplastic left heart syndrome (HLHS) remains a lethal congenital cardiac
defect. Recent studies have suggested that intracoronary administration of autologous …

Almost fifty years after its first clinical application, the modified Fontan operation is among
the most frequently performed procedures in congenital heart disease surgery in children …

Aim We now know that 20–40% of patients with a single ventricle will develop heart failure
after the second decade post-Fontan surgery. However, we remain unable to risk-stratify the …