Chinese herbal medicine meets biological networks of complex diseases: a computational perspective

S Gu, J Pei - Evidence‐Based Complementary and Alternative …, 2017 - Wiley Online Library
With the rapid development of cheminformatics, computational biology, and systems biology,
great progress has been made recently in the computational research of Chinese herbal …

[HTML][HTML] Uses of Molecular Docking Simulations in Elucidating Synergistic, Additive, and/or Multi-Target (SAM) Effects of Herbal Medicines

SP Rigby - Molecules, 2024 - mdpi.com
The philosophy of herbal medicines is that they contain multiple active components that
target many aspects of a given disease. This is in line with the recent multiple-target strategy …

Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors

M Zhang, R Singh, S Peng, T Mazumdar… - Cancer letters, 2017 - Elsevier
The genomic alterations identified in head and neck squamous cell carcinoma (HNSCC)
tumors have not resulted in any changes in clinical care, making the development of …

Predicting angiogenic receptor trafficking and signaling via computational systems biology

JC Weddell - 2016 - ideals.illinois.edu
Angiogenesis is defined as the growth of new blood vessels from preexisting vessels.
Systematic regulation of angiogenesis could lead to new treatments of vascular diseases …