Integration of GC–MS and LC–MS for untargeted metabolomics profiling

ÖC Zeki, CC Eylem, T Reçber, S Kır… - Journal of Pharmaceutical …, 2020 - Elsevier
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …

Industrial production of organophosphate flame retardants (OPFRs): big knowledge gaps need to be filled?

J Huang, L Ye, M Fang, G Su - Bulletin of Environmental Contamination …, 2022 - Springer
Since the phase-out of traditional halogenated flame retardants (HFRs), interests of research
are gradually being shifted to organophosphate flame retardants (OPFRs), and this can be …

[HTML][HTML] Exposure to a mixture of legacy, alternative, and replacement per-and polyfluoroalkyl substances (PFAS) results in sex-dependent modulation of cholesterol …

K Roth, Z Yang, M Agarwal, W Liu, Z Peng… - Environment …, 2021 - Elsevier
Background Epidemiological studies have shown Per-and polyfluoroalkyl substances
(PFAS) to be associated with diseases of dysregulated lipid and sterol homeostasis such as …

[HTML][HTML] Per-and polyfluoroalkyl substance (PFAS) exposure, maternal metabolomic perturbation, and fetal growth in African American women: A meet-in-the-middle …

CJ Chang, DB Barr, PB Ryan, P Panuwet… - Environment …, 2022 - Elsevier
Background Prenatal exposures to per-and polyfluoroalkyl substances (PFAS) have been
linked to reduced fetal growth. However, the detailed molecular mechanisms remain largely …

[HTML][HTML] Non-targeted metabolomics and associations with per-and polyfluoroalkyl substances (PFAS) exposure in humans: A scoping review

P Guo, T Furnary, V Vasiliou, Q Yan, K Nyhan… - Environment …, 2022 - Elsevier
Objective To summarize the application of non-targeted metabolomics in epidemiological
studies that assessed metabolite and metabolic pathway alterations associated with per-and …

[HTML][HTML] Associations of per-and polyfluoroalkyl substances (PFAS) and their mixture with oxidative stress biomarkers during pregnancy

KR Taibl, S Schantz, MT Aung, A Padula… - Environment …, 2022 - Elsevier
Background Oxidative stress from excess reactive oxygen species (ROS) is a hypothesized
contributor to preterm birth. Per-and polyfluoroalkyl substances (PFAS) exposure is reported …

Metabolic signatures of youth exposure to mixtures of per-and polyfluoroalkyl substances: a multi-cohort study

JA Goodrich, DI Walker, J He, X Lin… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Exposure to per-and polyfluoroalkyl substances (PFAS) is ubiquitous and has
been associated with an increased risk of several cardiometabolic diseases. However, the …

Covalent organic frameworks-based solid-phase microextraction probe for rapid and ultrasensitive analysis of trace per-and polyfluoroalkyl substances using mass …

YJ Hou, J Deng, K He, C Chen, Y Yang - Analytical Chemistry, 2020 - ACS Publications
Rapid and ultrasensitive analysis of trace pollutants in complex matrices is of significance for
understanding their environmental behaviors and toxic effects. Here a novel method based …

[HTML][HTML] A review of omics-based PFAS exposure studies reveals common biochemical response pathways

DJ Beale, GM Sinclair, R Shah, AM Paten… - Science of The Total …, 2022 - Elsevier
Abstract Per and Polyfluoroalkyl Substances (PFAS) are a diverse group of man-made
chemicals with a range of industrial applications and which are widespread in the …

[HTML][HTML] Metabolic perturbations in pregnant rats exposed to low-dose perfluorooctanesulfonic acid: an integrated multi-omics analysis

G Yu, J Wang, Y Liu, T Luo, X Meng, R Zhang… - Environment …, 2023 - Elsevier
Emerging epidemiological evidence has linked per-and polyfluoroalkyl substances (PFAS)
exposure could be linked to the disturbance of gestational glucolipid metabolism, but the …