Abstract l-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for
degradation by β-oxidation. Treatment with l-carnitine can ameliorate metabolic imbalances …

Mitochondrial fatty acid oxidation (FAO) plays a pivotal role in maintaining body energy
homoeostasis mainly during catabolic states. Oxidation of fatty acids requires approximately …

Micropeptide regulator of β-oxidation (MOXI) is a conserved muscle-enriched protein
encoded by an RNA transcript misannotated as non-coding. MOXI localizes to the inner …

In recent years increasing evidence has emerged suggesting that oxidative stress is
involved in the pathophysiology of a number of inherited metabolic disorders. However the …

CD 8+ T cells are key members of the adaptive immune response against infections and
cancer. As we discuss in this review, these cells can present diverse metabolic …

Fatty acid oxidation disorders (FAODs) are inborn errors of metabolism (IEMs) caused by
defects in the fatty acid (FA) mitochondrial β-oxidation. The most common FAODs are …

Fatty liver disease is epidemiologically associated with type 2 diabetes (T2D), leading to a
speculation of a reciprocal cause–effect relationship and a vicious cycle of pathology. Here …

The liver is critical for maintaining systemic energy balance during starvation. To understand
the role of hepatic fatty acid β-oxidation on this process, we generated mice with a liver …

The impaired capacity of skeletal muscle to switch between the oxidation of fatty acid (FA)
and glucose is linked to disordered metabolic homeostasis. To understand how muscle FA …

Background & Aims Although the role of inflammation to combat infection is known, the
contribution of metabolic changes in response to sepsis is poorly understood. Sepsis …