A collicular map for touch-guided tongue control

BS Ito, Y Gao, B Kardon, JH Goldberg - Nature, 2025 - nature.com
Accurate goal-directed behaviour requires the sense of touch to be integrated with
information about body position and ongoing motion,. Behaviours such as chewing …

Effects of reward and effort history on decision making and movement vigor during foraging

S Sukumar, R Shadmehr… - Journal of …, 2024 - journals.physiology.org
During foraging, animals explore a site and harvest reward and then abandon that site and
travel to the next opportunity. One aspect of this behavior involves decision making, and the …

Complex spikes perturb movements and reveal the sensorimotor map of Purkinje cells

SZ Muller, JS Pi, P Hage, MA Fakharian… - Current Biology, 2023 - cell.com
Computations that are performed by the cerebellar cortex are transmitted via simple spikes
of Purkinje cells (P-cells) to downstream structures, but because P-cells are many synapses …

The olivary input to the cerebellum dissociates sensory events from movement plans

JS Pi, MA Fakharian, P Hage… - Proceedings of the …, 2024 - National Acad Sciences
Neurons in the inferior olive are thought to anatomically organize the Purkinje cells (P-cells)
of the cerebellum into computational modules, but what is computed by each module? Here …

Control of tongue movements by the Purkinje cells of the cerebellum

P Hage, MA Fakharian, AM Shoup, JS Pi… - bioRxiv, 2024 - biorxiv.org
To quantify the cerebellum's contributions to control of the tongue, we trained head-fixed
marmosets to make dexterous movements, harvesting food from small tubes that were …

A vector calculus for neural computation in the cerebellum

MA Fakharian, A Shoup, P Hage, H Elseweifi… - bioRxiv, 2024 - biorxiv.org
When a neuron modulates its firing rate during a movement, we tend to assume that it is
contributing to control of that movement. However, null space theory makes the counter …

On the Determinants of the History-Dependent Modulation of Motor Control and Decision-Making

S Sukumar - 2023 - search.proquest.com
Most decisions we make are realized through movements and how we make these
movements determine the outcomes of our decisions. In this thesis, I present an augmented …