Genetic load: genomic estimates and applications in non-model animals

G Bertorelle, F Raffini, M Bosse, C Bortoluzzi… - Nature Reviews …, 2022 - nature.com
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

Demography and its effects on genomic variation in crop domestication

BS Gaut, DK Seymour, Q Liu, Y Zhou - Nature plants, 2018 - nature.com
Over two thousand plant species have been modified morphologically through cultivation
and human use. Here, we review three aspects of crop domestication that are currently …

[HTML][HTML] Phylogenomic discovery of deleterious mutations facilitates hybrid potato breeding

Y Wu, D Li, Y Hu, H Li, GP Ramstein, S Zhou, X Zhang… - Cell, 2023 - cell.com
Hybrid potato breeding will transform the crop from a clonally propagated tetraploid to a
seed-reproducing diploid. Historical accumulation of deleterious mutations in potato …

Genetic costs of domestication and improvement

BT Moyers, PL Morrell, JK McKay - Journal of Heredity, 2018 - academic.oup.com
The “cost of domestication” hypothesis posits that the process of domesticating wild species
can result in an increase in the number, frequency, and/or proportion of deleterious genetic …

The patterns of deleterious mutations during the domestication of soybean

MS Kim, R Lozano, JH Kim, DN Bae, ST Kim… - Nature …, 2021 - nature.com
Globally, soybean is a major protein and oil crop. Enhancing our understanding of the
soybean domestication and improvement process helps boost genomics-assisted breeding …

Evolutionary dynamics and adaptive benefits of deleterious mutations in crop gene pools

SL Dwivedi, P Heslop-Harrison, C Spillane… - Trends in Plant …, 2023 - cell.com
Mutations with deleterious consequences in nature may be conditionally deleterious in crop
plants. That is, while some genetic variants may reduce fitness under wild conditions and be …

Soybean (Glycine max) Haplotype Map (GmHapMap): a universal resource for soybean translational and functional genomics

D Torkamaneh, J Laroche, B Valliyodan… - Plant biotechnology …, 2021 - Wiley Online Library
Here, we describe a worldwide haplotype map for soybean (GmHapMap) constructed using
whole‐genome sequence data for 1007 Glycine max accessions and yielding 14.9 million …

Fitness effects of mutations: an assessment of PROVEAN predictions using mutation accumulation data

L Sandell, NP Sharp - Genome biology and evolution, 2022 - academic.oup.com
Predicting fitness in natural populations is a major challenge in biology. It may be possible to
leverage fast-accumulating genomic data sets to infer the fitness effects of mutant alleles …

Deleterious Mutations Accumulate Faster in Allopolyploid Than Diploid Cotton (Gossypium) and Unequally between Subgenomes

JL Conover, JF Wendel - Molecular biology and evolution, 2022 - academic.oup.com
Whole-genome duplication (polyploidization) is among the most dramatic mutational
processes in nature, so understanding how natural selection differs in polyploids relative to …

Genetic structure and first genome‐wide insights into the adaptation of a wild relative of grapevine, Vitis berlandieri

L Blois, M de Miguel, PF Bert, N Girollet… - Evolutionary …, 2023 - Wiley Online Library
In grafted plants, such as grapevine, increasing the diversity of rootstocks available to
growers is an ideal strategy for helping plants to adapt to climate change. The rootstocks …