Biological networks for cancer candidate biomarkers discovery
Due to its extraordinary heterogeneity and complexity, cancer is often proposed as a model
case of a systems biology disease or network disease. There is a critical need of effective …
case of a systems biology disease or network disease. There is a critical need of effective …
A new decision tree to solve the puzzle of Alzheimer's disease pathogenesis through standard diagnosis scoring system
A Kumar, TR Singh - Interdisciplinary Sciences: Computational Life …, 2017 - Springer
Alzheimer's disease (AD) is a progressive, incurable and terminal neurodegenerative
disorder of the brain and is associated with mutations in amyloid precursor protein …
disorder of the brain and is associated with mutations in amyloid precursor protein …
Lmx1b is required for the glutamatergic fates of a subset of spinal cord neurons
WC Hilinski, JR Bostrom, SJ England… - Neural …, 2016 - Springer
Background Alterations in neurotransmitter phenotypes of specific neurons can cause
imbalances in excitation and inhibition in the central nervous system (CNS), leading to …
imbalances in excitation and inhibition in the central nervous system (CNS), leading to …
An interaction network driven approach for identifying biomarkers for progressing cervical intraepithelial neoplasia
Overlapping genes across high-grade squamous intraepithelial lesions (CIN2 and 3) and
cancer may serve as potential biomarkers for this progressive disease. Differentially …
cancer may serve as potential biomarkers for this progressive disease. Differentially …
[HTML][HTML] Computational approach for assessing the involvement of SMYD2 protein in human cancers using TCGA data
Background SMYD2 is a protein of the SET and MYND domain-containing family SMYD. It
can methylate the lysine residue of various histone and nonhistone cancer-related proteins …
can methylate the lysine residue of various histone and nonhistone cancer-related proteins …
Computational studies to explore the role of MSI associated DNA mismatch repair mechanisms in HNPCC through expression and interaction data
S Behl, A Sharma, P Suravajhala… - International Journal of …, 2020 - inderscienceonline.com
Microsatellite instability (MSI) is an error mechanism associated with DNA mismatch repair
(MMR) system constituting a set of genes. If MMR fails, MSI may lead to various forms of …
(MMR) system constituting a set of genes. If MMR fails, MSI may lead to various forms of …
Studies on DNA Repair Mechanism and Non-Small Cell Lung Cancer
N Khan, TR Singh - 2023 - ir.juit.ac.in
Human beings are exposed to a variety of DNA damaging compounds on a regular basis,
which can have an impact on their health and affect disease states. On the other hand, DNA …
which can have an impact on their health and affect disease states. On the other hand, DNA …
Fundamental and Best Practices for Protein Annotations
TR Singh, P Suravajhala - Bioinformatics and Computational Biology - taylorfrancis.com
During the last two decades, bioinformatics has seen contemporaneous growth with
massive genomic and proteomic data. A myriad of tools and servers have also been …
massive genomic and proteomic data. A myriad of tools and servers have also been …
Computational Network Approaches and Their Applications for Complex Diseases
Network biology has been widely used for the interaction studies and analysis in modern
era. Studies associated with biological networks, their modeling, analysis, and visualization …
era. Studies associated with biological networks, their modeling, analysis, and visualization …
[PDF][PDF] Machine Learning Based Cancer Type Classification Using NGS Data
A Malik, TR Singh - 2022 - ir.juit.ac.in
Cancer is the diseases where therapy sensitivity differs greatly between patients living at the
different regions [1]. However, thanks to tremendous developments in genetics and …
different regions [1]. However, thanks to tremendous developments in genetics and …