Glycoscience assembles all the scientific disciplines involved in studying various molecules
and macromolecules containing carbohydrates and complex glycans. Such an ensemble …

Complex carbohydrates are ubiquitous in nature, and together with proteins and nucleic
acids they comprise the building blocks of life. But unlike proteins and nucleic acids …

Here we have generated 3D structures of glycoforms of the spike (S) glycoprotein from
SARS-CoV-2, based on reported 3D structures and glycomics data for the protein produced …

The SARS-CoV-2 betacoronavirus uses its highly glycosylated trimeric Spike protein to bind
to the cell surface receptor angiotensin converting enzyme 2 (ACE2) glycoprotein and …

Highlights•Recent advancements in glycoinformatics tools to support analysis of glycan and
glycopeptide data sets are summarised.•Review summarises the growth of machine …

Galectins compose a protein family defined by a conserved sequence motif conferring
affinity for β-galactose–containing glycans. Moreover, galectins gain higher affinity and fine …

Characteristically, cells must sense and respond to environmental cues. Despite the
importance of cell–cell communication, our understanding remains limited and often lacks …

While glycans are crucial for biological processes, existing analysis modalities make it
difficult for researchers with limited computational background to include these diverse …

Analysis and systematization of accumulated data on carbohydrate structural diversity is a
subject of great interest for structural glycobiology. Despite being a challenging task …

The cation-independent mannose 6-phosphate receptor (CI-MPR, IGF2 receptor or CD222),
is a multifunctional glycoprotein required for normal development. Through the receptor's …