Antibacterial designs for implantable medical devices: Evolutions and challenges

H Cao, S Qiao, H Qin, KD Jandt - Journal of Functional Biomaterials, 2022 - mdpi.com
The uses of implantable medical devices are safer and more common since sterilization
methods and techniques were established a century ago; however, device-associated …

Metal Ion-Doped Hydroxyapatite-Based Materials for Bone Defect Restoration

X Wang, S Huang, Q Peng - Bioengineering, 2023 - mdpi.com
Hydroxyapatite (HA)-based materials are widely used in the bone defect restoration field
due to their stable physical properties, good biocompatibility, and bone induction potential …

[HTML][HTML] Antibacterial activity of silver doped hydroxyapatite toward multidrug-resistant clinical isolates of Acinetobacter baumannii

T Ivankovic, H Turk, J Hrenovic, Z Schauperl… - Journal of hazardous …, 2023 - Elsevier
Bacteria Acinetobacter baumannii is a persistent issue in hospital-acquired infections due to
its fast and potent development of multi-drug resistance. To address this urgent challenge, a …

Palladium (II) Metal Complex Fabricated Titanium Implant Mitigates Dual-Species Biofilms in Artificial Synovial Fluid

S Jothipandiyan, D Suresh, S Sekaran… - Antibiotics, 2023 - mdpi.com
Metallodrugs have a potent application in various medical fields. In the current study, we
used a novel Palladium (II) thiazolinyl picolinamide complex that was directly fabricated over …

Prosthetic Knee Joint Infection Due to Candida lusitaniae: A Diagnostic and Therapeutic Odyssey: A Case Study

V Giovanoulis, AV Vasiliadis, C Koutserimpas… - Diagnostics, 2022 - mdpi.com
Prosthetic joint infections (PJIs) caused by fungi, although relatively rare, represent a major
surgery-related complication. An extremely rare fungal PJI, following revised total knee …

[HTML][HTML] High-concentration continuous local antibacterial perfusion therapy: safety and potential efficacy for acute and chronic periprosthetic knee joint infection

Y Suzuki, K Iwasaki, Z Joutoku, T Onodera… - SICOT …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Periprosthetic joint infections (PJIs) following total knee arthroplasty (TKA) are
among the most challenging pathologies to manage. Recently, continuous local antibiotic …

[HTML][HTML] Bacterial pathogens in orthopedic implant infection and their resistance to antimicrobial therapy: A retrospective analysis

AHMU Hassan, N Nooz, H Ashraf… - Journal of Orthopaedic …, 2025 - Elsevier
Background Orthopedic implant infections pose a significant challenge in healthcare due to
increasing rates and the emergence of multidrug-resistant (MDR) pathogens. This study …

Silver Carboxylate-Eluting Titanium-Dioxide Polydimethylsiloxane Coating Inhibits Multi-Drug–Resistant Acinetobacterium baumannii and Vancomycin-Resistant …

DR Garcia, N Vishwanath, A Minnah, S Allu… - Surgical …, 2022 - liebertpub.com
Background: Vancomycin-resistant Enterococcus faecalis and multi-drug–resistant (MDR)
Acinetobacter baumannii are rising contributors to spinal fusion and fracture-associated …

Changes of the microbiological spectrum and antibiotic resistance pattern in postoperative spinal implant infections with multiple culture-positive revision surgeries

JA Mitterer, BJH Frank, S Gardete-Hartmann… - The Spine Journal, 2022 - Elsevier
BACKGROUND CONTEXT In severe cases of postoperative spinal implant infections (PSII)
multiple revision surgeries may be needed. Little is known if changes in the microbiological …