Immune response to infection with Salmonella typhimurium in mice

HW Mittrücker, SHE Kaufmann - Journal of leukocyte biology, 2000 - academic.oup.com
Infection of mice with Salmonella typhimurium results in systemic infection and a disease
similar to that seen in humans after infection with S. typhi. The innate immune system can …

Revisiting Persistent Salmonella Infection and the Carrier State: What Do We Know?

N Foster, Y Tang, A Berchieri, S Geng, X Jiao, P Barrow - Pathogens, 2021 - mdpi.com
One characteristic of the few Salmonella enterica serovars that produce typhoid-like
infections is that disease-free persistent infection can occur for months or years in a small …

Signaling via the MyD88 adaptor protein in B cells suppresses protective immunity during Salmonella typhimurium infection

P Neves, V Lampropoulou, E Calderon-Gomez, T Roch… - Immunity, 2010 - cell.com
The myeloid differentiation primary response gene 88 (Myd88) is critical for protection
against pathogens. However, we demonstrate here that MyD88 expression in B cells inhibits …

Risk factors for typhoid and paratyphoid fever in Jakarta, Indonesia

AM Vollaard, S Ali, HAGH Van Asten, S Widjaja… - Jama, 2004 - jamanetwork.com
ContextThe proportion of paratyphoid fever cases to typhoid fever cases may change due to
urbanization and increased dependency on food purchased from street vendors. For …

Salmonella typhi, the causative agent of typhoid fever, is approximately 50,000 years old

C Kidgell, U Reichard, J Wain, B Linz… - Infection, Genetics and …, 2002 - Elsevier
A global collection of 26 isolates of Salmonella typhi was investigated by sequencing a total
of 3336bp in seven housekeeping genes. Only three polymorphic sites were found and the …

Evaluation of rapid diagnostic tests for typhoid fever

SJ Olsen, J Pruckler, W Bibb, NTM Thanh… - Journal of clinical …, 2004 - Am Soc Microbiol
Laboratory diagnosis of typhoid fever requires isolation and identification of Salmonella
enterica serotype Typhi. In many areas where this disease is endemic, laboratory capability …

A mouse model for the human pathogen Salmonella typhi

J Song, T Willinger, A Rongvaux, EE Eynon… - Cell host & …, 2010 - cell.com
Salmonella enterica serovar Typhi (S. Typhi) causes typhoid fever, a life-threatening human
disease. The lack of animal models due to S. Typhi's strict human host specificity has …

Quantitation of bacteria in bone marrow from patients with typhoid fever: relationship between counts and clinical features

J Wain, PVB Bay, HA Vinh, NM Duong… - Journal of clinical …, 2001 - Am Soc Microbiol
Enteric fever is the only bacterial infection of humans for which bone marrow examination is
routinely recommended. A prospective study of the concentrations of bacteria in the bone …

Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1

CE Stebbins, JE Galán - Molecular cell, 2000 - cell.com
Salmonella spp. utilize a specialized protein secretion system to deliver a battery of effector
proteins into host cells. Several of these effectors stimulate Cdc42-and Rac1-dependent …

The molecular mechanisms of severe typhoid fever

P Everest, J Wain, M Roberts, G Rook, G Dougan - Trends in Microbiology, 2001 - cell.com
Salmonella typhi continues to cause severe disease in many parts of the world, its most
feared complication being perforation of ulcerated Peyer's patches within the small intestine …