Cognitive impairment is an increasingly recognized major cause of chronic disability and is
commonly found in patients with chronic kidney disease (CKD). Knowledge of the …

Background White matter hyperintensities (WMH) are very frequent in older adults and
associated with worse cognitive performance. Little is known about the links between WMH …

Introduction Impact of white matter hyperintensities (WMH) on cognition likely depends on
lesion location, but a comprehensive map of strategic locations is lacking. We aimed to …

Neuroimaging features of small vessel disease (SVD) are highly prevalent in older
adulthood and associated with significant variability in clinical symptoms, yet the factors …

Objectives: To assess in a large population of patients with clinically isolated syndrome
(CIS) the relevance of brain lesion location and frequency in predicting 1-year conversion to …

Objective To investigate the association of chronic obstructive pulmonary disease (COPD)
and Preserved Ratio Impaired Spirometry (PRISm) with cognitive performance and …

Background Vascular mild cognitive impairment (VMCI) is a transitional condition that may
evolve into Vascular Dementia (VaD). Hippocampal volume (HV) is suggested as an early …

Cerebral small vessel disease (CSVD) is a pathophysiological process involving small
arteries such as cerebellar arteries, arterioles, capillaries, and veinlets. Imaging features …

Background The relative contribution of changes in the cerebral white matter (WM) and
cortical gray matter (GM) to the transition to dementia in patients with mild cognitive …

Epidemiological studies have linked age-related hearing loss (ARHL) with an increased risk
of neurocognitive decline. Difficulties in speech perception with subsequent changes in …