Cancer is a leading cause of death worldwide. Surgery is the primary treatment approach for
cancer, but the survival rate is very low due to the rapid progression of the disease and …

Urological cancers are among the most common malignancies around the world. In
particular, bladder cancer severely threatens human health due to its aggressive and …

Purpose The overall response of cisplatin-based chemotherapy in bladder urothelial
carcinoma (BUC) remains unsatisfactory due to the complex pathological subtypes, genomic …

Purpose: Resistance to cisplatin-based chemotherapy is a major obstacle to bladder cancer
treatment. We aimed to identify microRNAs (miRNA) that are dysregulated in cisplatin …

Cisplatin-based chemotherapeutic regimens are the most frequently used (neo) adjuvant
treatments for the majority of solid tumors. While platinum-based chemotherapeutic …

The tumor microenvironment (TME) serves as a multidrug resistant center for tumors under
the assault of chemotherapy and a physiological barrier against the penetration of …

Encapsulation of cisplatin (CDDP) into nanoparticles (NPs) with high drug loading and
encapsulation efficiency has been difficult due to the poor solubility of CDDP. However, this …

Simple Summary Urothelial bladder carcinoma entails significant health costs due to the
high recurrence rates and poor response to standard cisplatin-based treatment. The …

Chemoresistance to cisplatin is a principal cause of treatment failure and mortality of
advanced bladder cancer (BC). The underlying mechanisms remain unclear, which hinders …

Heterogeneous nuclear ribonucleoprotein K (hn RNPK) is an essential RNA‐and DNA‐
binding protein that regulates diverse biological events, especially DNA transcription. hn …