Direct and indirect effects of sex steroids on gonadotrope cell plasticity in the teleost fish pituitary

R Fontaine, MR Royan, K Von Krogh… - Frontiers in …, 2020 - frontiersin.org
The pituitary gland controls many important physiological processes in vertebrates,
including growth, homeostasis, and reproduction. As in mammals, the teleost pituitary …

Development of the pituitary gland

KS Alatzoglou, LC Gregory… - Comprehensive …, 2020 - discovery.ucl.ac.uk
The development of the anterior pituitary gland occurs in distinct sequential developmental
steps, leading to the formation of a complex organ containing five different cell types …

Sexually dimorphic regulation of gonadotrope cell hyperplasia in medaka pituitary via mitosis and transdifferentiation

MR Royan, D Kayo, FA Weltzien, R Fontaine - Endocrinology, 2023 - academic.oup.com
The 2 pituitary gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone
(LH), regulate the reproductive function in all vertebrates. While many studies have …

Advancing thyroid disease research: The role and potential of zebrafish model

J Qu, Y Fang, R Tao, J Zhao, T Xu, R Chen, J Zhang… - Life Sciences, 2024 - Elsevier
Thyroid disorders significantly affect human metabolism, cardiovascular function, skeletal
health, and reproductive systems, presenting a complex challenge due to their multifactorial …

Characterization of hormone-producing cell types in the teleost pituitary gland using single-cell RNA-seq

K Siddique, E Ager-Wick, R Fontaine, FA Weltzien… - Scientific Data, 2021 - nature.com
The pituitary is the vertebrate endocrine gland responsible for the production and secretion
of several essential peptide hormones. These, in turn, control many aspects of an animal's …

3D Atlas of the Pituitary Gland of the Model Fish Medaka (Oryzias latipes)

MR Royan, K Siddique, G Csucs… - Frontiers in …, 2021 - frontiersin.org
In vertebrates, the anterior pituitary plays a crucial role in regulating several essential
physiological processes via the secretion of at least seven peptide hormones by different …

[HTML][HTML] Gonadotrope plasticity at cellular, population and structural levels: A comparison between fishes and mammals

R Fontaine, E Ciani, TM Haug, K Hodne… - General and …, 2020 - Elsevier
Often referred to as “the master gland”, the pituitary is a key organ controlling growth,
maturation, and homeostasis in vertebrates. The anterior pituitary, which contains several …

Unconventional actions of glycoprotein hormone subunits: A comprehensive review

B Querat - Frontiers in Endocrinology, 2021 - frontiersin.org
The glycoprotein hormones (GPH) are heterodimers composed of a common α subunit and
a specific β subunit. They act by activating specific leucine-rich repeat G protein-coupled …

[HTML][HTML] Pituitary multi-hormone cells in mammals and fish: history, origin, and roles

R Fontaine, MR Royan, C Henkel, K Hodne… - Frontiers in …, 2022 - Elsevier
The vertebrate pituitary is a dynamic organ, capable of adapting its hormone secretion to
different physiological demands. In this context, endocrinologists have debated for the past …

Plasticity of Lh cells caused by cell proliferation and recruitment of existing cells

R Fontaine, E Ager-Wick, K Hodne… - Journal of …, 2019 - joe.bioscientifica.com
Luteinizing hormone (Lh) and follicle-stimulating hormone (Fsh) control reproduction in
vertebrates. Using a transgenic line of medaka, in which green fluorescent protein …