Host defense peptides as immunomodulators: The other side of the coin

EM Martell, M Gonzalez-Garcia, L Ständker… - Peptides, 2021 - Elsevier
Host defense peptides (HDPs) exhibit a broad range of antimicrobial and
immunomodulatory activities. In this sense, both functions are like different sides of the same …

Natural Amphibian-Derived Host Defense Peptides: Peptide Immunomodulators with Potential Therapeutic Value

J Shi, J Wu, G Feng, H Yang… - Protein and Peptide Letters, 2023 - ingentaconnect.com
Due to the rapid evolution of bacterial drug resistance, anti-infective treatment has become a
global problem. Therefore, there is an urgent need to develop alternative treatment …

Structure and function of cationic hylin bioactive peptides from the tree frog Boana pulchella in interaction with lipid membranes

S Aguilar, AE Brunetti, AV Garay, LC Santos, LO Perez… - Peptides, 2023 - Elsevier
Amphibians have a great diversity of bioactive peptides in their skin. The cDNA prepro-
peptide sequencing allowed the identification of five novel mature peptides expressed in the …

Anti-Inflammatory Activity of a Peptide from Skipjack (Katsuwonus pelamis)

Z Wang, X Ying, P Gao, C Wang, Y Wang, X Yu, J Chen… - Marine drugs, 2019 - mdpi.com
In this paper, the effect of skipjack (Katsuwonus pelamis) enzymatic peptide (SEP), which
was prepared and purified from a byproduct of skipjack, on inflammation, ulcerative colitis …

Biological Properties of a Novel Multifunctional Host Defense Peptide from the Skin Secretion of the Chaco Tree Frog, Boana raniceps

CJC Santana, ACM Magalhães, CA Prías-Márquez… - Biomolecules, 2020 - mdpi.com
In recent years, the number of new antimicrobial drugs launched on the market has
decreased considerably even though there has been an increase in the number of resistant …

Anti-inflammatory peptide therapeutics and the role of sulphur containing amino acids (cysteine and methionine) in inflammation suppression: A review

CA Biji, A Balde, RA Nazeer - Inflammation Research, 2024 - Springer
Background Inflammation serves as our body's immune response to combat infections,
pathogens, viruses, and external stimuli. Inflammation can be classified into two types: acute …

BR-bombesin: a novel bombesin-related peptide from the skin secretion of the Chaco tree frog (Boana raniceps) with physiological gastric effects

NA de Sousa, MM Marani, ALF Lopes, EM Silva… - Amino Acids, 2022 - Springer
Bombesin mediates several biological activities in the gastrointestinal (GI) tract and central
nervous system in mammals, including smooth muscle contraction, secretion of GI hormones …

A first look at the N-and O-glycosylation landscape in anuran skin secretions

EA Barbosa, GSC Alves, MMA Coura, HL e Silva… - Biochimie, 2022 - Elsevier
Amphibians secrete a complex array of molecules that shape their interactions with
coinhabiting microorganisms and macroscopic predators. Glycans are a rapidly evolving …

Antimicrobial peptides: Features and modes of action

F Francis, N Chaudhary - Antimicrobial Peptides, 2023 - Elsevier
Antimicrobial peptides (AMPs) or host defense peptides are short amphipathic, generally
cationic, evolutionarily conserved biomolecules that constitute the first line of defense in …

An experimental protocol for molecular biology lab at an Amazonian University

F Valdivieso‐Rivera, JR Almeida… - Biochemistry and …, 2022 - Wiley Online Library
Laboratory‐based practical classes are an essential component in teaching molecular
biology for undergraduate students. Universidad Regional Amazonica Ikiam is a higher …