Lipid-based delivery systems for flavonoids and flavonolignans: liposomes, nanoemulsions, and solid lipid nanoparticles

S Ranjbar, A Emamjomeh, F Sharifi, A Zarepour… - Pharmaceutics, 2023 - mdpi.com
Herbal chemicals with a long history in medicine have attracted a lot of attention.
Flavonolignans and flavonoids are considered as two classes of the above-mentioned …

Dendrimers as nanocarriers for the delivery of drugs obtained from natural products

H An, X Deng, F Wang, P Xu, N Wang - Polymers, 2023 - mdpi.com
Natural products have proven their value as drugs that can be therapeutically beneficial in
the treatment of various diseases. However, most natural products have low solubility and …

Silibinin attenuates experimental periodontitis by downregulation of inflammation and oxidative stress

X Li, R Zhou, Y Han, J Zeng, L Shi… - Oxidative medicine …, 2023 - Wiley Online Library
Periodontitis is an oral microbiota‐induced inflammatory disease, in which inflammation and
oxidative stress play a critical role. Silibinin (SB), a Silybum marianum‐derived compound …

Investigation of Cardioprotective Activity of Silybin: Network Pharmacology, Molecular Docking, and In Vivo Studies

P Kumar Pasala, M Donakonda, PS Dintakurthi… - …, 2023 - Wiley Online Library
The abundant health benefits of silybin are known to benefit people with myocardial
infarction (MI). However, their mechanisms of action are not precise. To address this …

Silibinin alleviates DNA damage, mitochondrial dysfunction, and apoptosis caused by oxidative stress in human retinal pigment epithelial cells

YH Choi - Molecular & Cellular Toxicology, 2024 - Springer
Background Silibinin, a flavonolignan, is known to have a variety of pharmacological
activities, including antioxidant activity, but its antioxidant mechanism in the eye is unclear …

Thermochemical transition in low molecular weight substances: The example of the silybin flavonoid

C Tsioptsias, C Spartali, SI Marras, X Ntampou… - Molecules, 2022 - mdpi.com
Silybin is a complex organic molecule with high bioactivity, extracted from the plant Silybum.
As a pharmaceutical substance, silybin's bioactivity has drawn considerable attention, while …

Treatment of animals with fatty liver disease using a drug based on the seeds of Silybum marianum

V Vlizlo, O Prystupa, L Slivinska, B Gutyj… - Regulatory …, 2023 - medicine.dp.ua
Medicinal plants are a source of various therapeutic preparations. Therefore, the aim of our
work was to prepare a liposomal drug from extract from the seeds of Silybum marianum (L.) …

[HTML][HTML] Antiviral and immunostimulatory effects of Ssanti-Covir, a mixed herbal formulation, in cyclophosphamide-treated mice

MN Pham, PT Nguyen-Dung, VH Tran… - Pharmacological …, 2023 - Elsevier
Background The novel coronavirus disease 2019 (COVID-19) has raised many concerns
among populations worldwide due to its high mortality and morbidity with the lack of …

水飞蓟宾胶囊联合多烯磷脂酰胆碱治疗抗结核药物所致药物性肝损伤患者疗效研究

莫俊俏, 林景, 羊莉 - 实用肝脏病杂志, 2023 - manu43.magtech.com.cn
目的观察应用水飞蓟宾胶囊联合多烯磷脂酰胆碱治疗抗结核药物所致药物性肝损伤(DILI)
患者的疗效. 方法2018 年6 月~ 2021 年6 月我院收治的118 例肺结核患者, 经标准抗痨治疗后 …

水飞蓟素对副溶血性弧菌的抑制作用.

王珍, 秦宁波, 夏效东 - Journal of Food Safety & Quality, 2022 - search.ebscohost.com
目的研究水飞蓟素对副溶血性弧菌的抑制作用及可能的作用机制. 方法通过琼脂板稀释法和肉汤
稀释法确定水飞蓟素对两株菌(Vibrio parahaemolyticus ATCC17802 和V. parahaemolyticus …