[HTML][HTML] Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I: C) rat model
Neuropsychiatric disorders such as schizophrenia are associated with cognitive impairment,
including learning, memory and attention deficits. Antipsychotic drugs are limited in their …
including learning, memory and attention deficits. Antipsychotic drugs are limited in their …
Prenatal poly I: C challenge affects behaviors and neurotransmission via elevated neuroinflammation responses in female juvenile rats
Y Su, J Lian, J Hodgson, W Zhang… - International Journal of …, 2022 - academic.oup.com
Background Exposure to polyriboinosinic-polyribocytidylic acid (Poly I: C) in pregnant rats
has been reported to cause schizophrenia-like behaviors and abnormal neurotransmissions …
has been reported to cause schizophrenia-like behaviors and abnormal neurotransmissions …
Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I: C) model of neurodevelopmental …
Cognitive impairment is a major source of disability in schizophrenia and current
antipsychotic drugs (APDs) have minimal efficacy for this symptom domain. Cannabidiol …
antipsychotic drugs (APDs) have minimal efficacy for this symptom domain. Cannabidiol …
[HTML][HTML] Intake of 7, 8-dihydroxyflavone during juvenile and adolescent stages prevents onset of psychosis in adult offspring after maternal immune activation
Prenatal infection and subsequent abnormal neurodevelopment of offspring is involved in
the etiology of schizophrenia. Brain-derived neurotrophic factor (BDNF) and its high affinity …
the etiology of schizophrenia. Brain-derived neurotrophic factor (BDNF) and its high affinity …
[HTML][HTML] From neuroleptics to neuroscience and from Pavlov to psychotherapy: more than just the “emperor's new treatments” for mental illnesses?
J Margraf, S Schneider - EMBO molecular medicine, 2016 - embopress.org
“The drugs don't work” was one of the hit singles from The Verve's album Urban Hymns,
released in 1997. The song was written by lead singer Richard Ashcroft relating to his drug …
released in 1997. The song was written by lead singer Richard Ashcroft relating to his drug …
The long-lasting effects of early antipsychotic exposure during juvenile period on adult behaviours–A study in a poly I: C rat model
Second generation antipsychotic drugs including aripiprazole, olanzapine and risperidone
are prescribed increasingly (mostly off-label) to treat various mental disorders in children …
are prescribed increasingly (mostly off-label) to treat various mental disorders in children …
Early antipsychotic exposure affects serotonin and dopamine receptor binding density differently in selected brain loci of male and female juvenile rats
Abstract Background Antipsychotic drugs (APDs) were developed to treat schizophrenia in
adults; however they have been increasingly prescribed (mostly “off-label”) for children and …
adults; however they have been increasingly prescribed (mostly “off-label”) for children and …
Early-life risperidone alters locomotor responses to apomorphine and quinpirole in adulthood.
ME Bardgett, MS Griffith, KR Robinson… - Behavioural Brain …, 2024 - Elsevier
An escalating trend of antipsychotic drug use in children with ADHD, disruptive behavior
disorder, or mood disorders has raised concerns about the impact of these drugs on brain …
disorder, or mood disorders has raised concerns about the impact of these drugs on brain …
Chronic risperidone administration leads to greater amphetamine-induced conditioned place preference
ME Bardgett, T Downnen, C Crane, ECB Thompson… - …, 2020 - Elsevier
Risperidone is an atypical antipsychotic drug used increasingly in children to manage
symptoms of ADHD and conduct disorder. In rats, developmental risperidone administration …
symptoms of ADHD and conduct disorder. In rats, developmental risperidone administration …
[HTML][HTML] Brown adipose tissue activity is modulated in olanzapine-treated young rats by simvastatin
X Liu, X Feng, C Deng, L Liu, Y Zeng, CH Hu - BMC Pharmacology and …, 2020 - Springer
Background Prescription of second-generation antipsychotic drugs (SGAs) to
childhood/adolescent has exponentially increased in recent years, which was associated …
childhood/adolescent has exponentially increased in recent years, which was associated …