The control of sexual differentiation of the reproductive system and brain

CA Wilson, DC Davies - Reproduction, 2007 - rep.bioscientifica.com
This review summarizes current knowledge of the genetic and hormonal control of sexual
differentiation of the reproductive system, brain and brain function. While the chromosomal …

Influence of sex on sleep regulatory mechanisms

KN Paul, FW Turek, MH Kryger - Journal of women's health, 2008 - liebertpub.com
The ability of biological sex and sex-driven characteristics to alter sleep states may
contribute to gender disparities in sleep disorders. Sex influences sleep-wake amount, the …

Developmental fluoxetine exposure and prenatal stress alter sexual differentiation of the brain and reproductive behavior in male rat offspring

I Rayen, HWM Steinbusch, TD Charlier… - …, 2013 - Elsevier
Depression during pregnancy and postpartum is a significant health problem and affects up
to 20% of women. While selective serotonin reuptake inhibitor (SSRI) medications are the …

Paroxetine effects in adult male rat colon: Focus on gut steroidogenesis and microbiota

S Diviccaro, S Giatti, L Cioffi, E Falvo, R Piazza… - …, 2022 - Elsevier
Paroxetine, a selective serotonin reuptake inhibitor (SSRI), is prescribed to treat psychiatric
disorders, although an off-label SSRI use is also for functional gastrointestinal disorders …

Serotonin regulates prostate growth through androgen receptor modulation

E Carvalho-Dias, A Miranda, O Martinho, P Mota… - Scientific Reports, 2017 - nature.com
Aging and testosterone almost inexorably cause benign prostatic hyperplasia (BPH) in
Human males. However, etiology of BPH is largely unknown. Serotonin (5-HT) is produced …

Maternal exposure to the antidepressant fluoxetine impairs sexual motivation in adult male mice

TS Gouvêa, HK Morimoto, MJSS de Faria… - Pharmacology …, 2008 - Elsevier
Depressive disorders have a worldwide high prevalence. Fluoxetine (FLX), a selective
serotonin reuptake inhibitor (SSRI) antidepressant, has been widely prescribed for …

Lactational exposure to venlafaxine provokes late repercussions on reproductive parameters in male rat offspring

S da Silva Moreira, B de Matos Manoel… - Journal of Applied …, 2023 - Wiley Online Library
Exposure to selective serotonin reuptake inhibitors can affect hormone‐dependent
processes, such as the brain sexual differentiation. Because the use of these …

Low oral doses of bisphenol A increase volume of the sexually dimorphic nucleus of the preoptic area in male, but not female, rats at postnatal day 21

Z He, MG Paule, SA Ferguson - Neurotoxicology and teratology, 2012 - Elsevier
Perinatal treatment with relatively high doses of bisphenol A (BPA) appears to have little
effect on volume of the rodent sexually dimorphic nucleus of the preoptic area (SDN-POA) …

Could maternal exposure to the antidepressants fluoxetine and St. John's Wort induce long-term reproductive effects on male rats?

ML Vieira, RY Hamada, NI Gonzaga, AD Bacchi… - Reproductive …, 2013 - Elsevier
Based on the limited number of studies that have investigated the adverse effects of
maternal treatment with antidepressants on the development of male descendents, this …

Effects of developmental hyperserotonemia on juvenile play behavior, oxytocin and serotonin receptor expression in the hypothalamus are age and sex dependent

AMK Madden, SL Zup - Physiology & behavior, 2014 - Elsevier
There is a striking sex difference in the diagnosis of Autism Spectrum Disorder (ASD), such
that males are diagnosed more often than females, usually in early childhood. Given that …