BACKGROUND Autophagy is an intracellular catabolic process of degrading and recycling
proteins and organelles to modulate various physiological and pathological events …

Calcium (Ca2+) homeostasis is essential for cell maintenance since this ion participates in
many physiological processes. For example, the spatial and temporal organization of Ca2+ …

Spinal cord injury (SCI) can cause severe irreversible motor dysfunction and even death.
Neural stem cell (NSC) transplantation can promote functional recovery after acute SCI in …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Lysosomes are cell organelles that degrade macromolecules to recycle their components. If
lysosomal degradative function is impaired, eg, due to mutations in lysosomal enzymes or …

Autophagy is a lysosomal catabolic process essential to cell homeostasis and is related to
the neuroprotection of the central nervous system. Cannabidiol (CBD) is a non-psychotropic …

Autophagy is a cellular process in which the cell degrades and recycles its own constituents.
Given the crucial role of autophagy in physiology, deregulation of autophagic machinery is …

The family of coronaviruses (CoVs) uses the autophagy machinery of host cells to promote
their growth and replication; thus, this process stands out as a potential target to combat …

Pain is underdiagnosed and often not adequately treated, contributing to behavioral and
psychological symptoms of dementia (BPSD). BPSD are treated with atypical antipsychotics …

Lysosomal calcium is emerging as a modulator of autophagy and lysosomal compartment,
an obligatory partner to complete the autophagic pathway. A variety of specific signals such …