Genomic data often highlights an inconsistency between the number of gene clusters identified using bioinformatic approaches as potentially producing secondary metabolites …
R Pan, X Bai, J Chen, H Zhang, H Wang - Frontiers in Microbiology, 2019 - frontiersin.org
Microbial secondary metabolites (MSMs) have played and continue to play a highly significant role in the drug discovery and development process. Genetically, MSM chemical …
This review covers the literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for the period January to December 2015) referring to compounds …
In recent years, the search for novel natural compounds with bioactive properties has received a remarkable boost in view of their possible pharmaceutical exploitation. In this …
SH Akone, A Mándi, T Kurtán, R Hartmann, W Lin… - Tetrahedron, 2016 - Elsevier
Co-culturing the fungal endophyte Chaetomium sp. with the bacterium Bacillus subtilis on solid rice medium resulted in an up to 8.3-fold increase in the accumulation of constitutively …
CFP Hemphill, P Sureechatchaiyan… - The Journal of …, 2017 - nature.com
Abstract Using the OSMAC (One Strain MAny Compounds) approach, the fungal endophyte Fusarium tricinctum was cultivated on fruit and vegetable juice-supplemented solid rice …
S Liu, M Su, SJ Song, JH Jung - Marine drugs, 2017 - mdpi.com
Since the discovery of penicillin, Penicillium has become one of the most attractive fungal genera for the production of bioactive molecules. Marine-derived Penicillium has provided …
A Schüller, L Studt-Reinhold, J Strauss - Pharmaceutics, 2022 - mdpi.com
Fungal species have the capability of producing an overwhelming diversity of bioactive substances that can have beneficial but also detrimental effects on human health. These so …
MM Cheng, XL Tang, YT Sun, DY Song, YJ Cheng… - Molecules, 2020 - mdpi.com
Marine sponges are well known as rich sources of biologically natural products. Growing evidence indicates that sponges harbor a wealth of microorganisms in their bodies, which …