Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural product …, 2017 - pubs.rsc.org
Covering: 2015. Previous review: Nat. Prod. Rep., 2016, 33, 382–431 This review covers the
literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for …

Extending the “one strain many compounds”(OSMAC) principle to marine microorganisms

S Romano, SA Jackson, S Patry, ADW Dobson - Marine drugs, 2018 - mdpi.com
Genomic data often highlights an inconsistency between the number of gene clusters
identified using bioinformatic approaches as potentially producing secondary metabolites …

Exploring structural diversity of microbe secondary metabolites using OSMAC strategy: A literature review

R Pan, X Bai, J Chen, H Zhang, H Wang - Frontiers in Microbiology, 2019 - frontiersin.org
Microbial secondary metabolites (MSMs) have played and continue to play a highly
significant role in the drug discovery and development process. Genetically, MSM chemical …

[PDF][PDF] Natural product reports

JW Blunt, BR Copp, RA Keyzers, MH Munroa… - Nat Prod Rep, 2016 - academia.edu
This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …

Bioactive Compounds Produced by Strains of Penicillium and Talaromyces of Marine Origin

R Nicoletti, A Trincone - Marine drugs, 2016 - mdpi.com
In recent years, the search for novel natural compounds with bioactive properties has
received a remarkable boost in view of their possible pharmaceutical exploitation. In this …

Inducing secondary metabolite production by the endophytic fungus Chaetomium sp. through fungal–bacterial co-culture and epigenetic modification

SH Akone, A Mándi, T Kurtán, R Hartmann, W Lin… - Tetrahedron, 2016 - Elsevier
Co-culturing the fungal endophyte Chaetomium sp. with the bacterium Bacillus subtilis on
solid rice medium resulted in an up to 8.3-fold increase in the accumulation of constitutively …

OSMAC approach leads to new fusarielin metabolites from Fusarium tricinctum

CFP Hemphill, P Sureechatchaiyan… - The Journal of …, 2017 - nature.com
Abstract Using the OSMAC (One Strain MAny Compounds) approach, the fungal endophyte
Fusarium tricinctum was cultivated on fruit and vegetable juice-supplemented solid rice …

Marine-Derived Penicillium Species as Producers of Cytotoxic Metabolites

S Liu, M Su, SJ Song, JH Jung - Marine drugs, 2017 - mdpi.com
Since the discovery of penicillin, Penicillium has become one of the most attractive fungal
genera for the production of bioactive molecules. Marine-derived Penicillium has provided …

How to completely squeeze a fungus—advanced genome mining tools for novel bioactive substances

A Schüller, L Studt-Reinhold, J Strauss - Pharmaceutics, 2022 - mdpi.com
Fungal species have the capability of producing an overwhelming diversity of bioactive
substances that can have beneficial but also detrimental effects on human health. These so …

Biological and chemical diversity of marine sponge-derived microorganisms over the last two decades from 1998 to 2017

MM Cheng, XL Tang, YT Sun, DY Song, YJ Cheng… - Molecules, 2020 - mdpi.com
Marine sponges are well known as rich sources of biologically natural products. Growing
evidence indicates that sponges harbor a wealth of microorganisms in their bodies, which …