Sepsis is a common and lethal syndrome: although outcomes have improved, mortality
remains high. No specific anti-sepsis treatments exist; as such, management of patients …

The spread of extended-spectrum β-lactamase (ESBL) genes in Enterobacteriaceae such as
Escherichia coli or Klebsiella spp is a major challenge to modern medical practice …

Después del desarrollo y la comercialización en masa de los antibióticos, las bacterias
patógenas y ambientales han desa-rrollado resistencia a los antibióticos desde el siglo …

Las betalactamasas, enzimas con capacidad hidrolítica frente a los antibióticos
betalactámicos, son responsables del principal mecanismo de resistencia en bacterias …

Objectives To characterise the β-lactam, quinolone and macrolide resistance levels and
mechanisms in 62 Escherichia coli isolates causing bacteraemia in Peruvian children …

The production of β-lactamase is the principal mechanism by which gram-negative bacteria
resist the action of β-lactam antibiotics. In recent decades, there has been an alarming …

Objective: To assess the impact of sepsis classification and multidrug-resistance status on
outcome in patients receiving appropriate initial antibiotic therapy. Design: A retrospective …

Background The in vitro activity of tigecycline and comparator agents was evaluated against
Gram-positive and Gram-negative isolates collected in Latin American centers between …

Healthcare-related infections caused by extended-spectrum beta-lactamase (ESBL)-
producing Klebsiella spp. are of major concern. To control transmission, deep …

Nonetheless, there are no high-quality data from LMICs that can allow a better estimation.
Most studies, especially those from low-income settings, are retrospective and single center …