The physics of respiratory particle generation, fate in the air, and inhalation
Given that breathing is one of the most fundamental physiological functions, there is an
urgent need to broaden our understanding of the fluid dynamics that governs it. There would …
urgent need to broaden our understanding of the fluid dynamics that governs it. There would …
Anatomical Engineering and 3D printing for surgery and medical devices: International review and future exponential innovations
Three‐dimensional printing (3DP) has recently gained importance in the medical industry,
especially in surgical specialties. It uses different techniques and materials based on …
especially in surgical specialties. It uses different techniques and materials based on …
[HTML][HTML] Sex, gender and the pulmonary physiology of exercise
PB Dominelli, Y Molgat-Seon - European Respiratory Review, 2022 - Eur Respiratory Soc
In this review, we detail how the pulmonary system9s response to exercise is impacted by
both sex and gender in healthy humans across the lifespan. First, the rationale for why sex …
both sex and gender in healthy humans across the lifespan. First, the rationale for why sex …
iBCS: 1. Principles and framework of an inhalation-based biopharmaceutics classification system
JE Hastedt, P Bäckman, A Cabal, A Clark… - Molecular …, 2022 - ACS Publications
For oral drugs, the formulator and discovery chemist have a tool available to them that can
be used to navigate the risks associated with the selection and development of immediate …
be used to navigate the risks associated with the selection and development of immediate …
A pediatric upper airway library to evaluate interpatient variability of in silico aerosol deposition
The airway of pediatric patients' changes through development, presenting a challenge in
developing pediatric-specific aerosol therapeutics. Our work aims to quantify geometric …
developing pediatric-specific aerosol therapeutics. Our work aims to quantify geometric …
[HTML][HTML] A computed tomography imaging-based subject-specific whole-lung deposition model
The respiratory tract is an important route for beneficial drug aerosol or harmful particulate
matter to enter the body. To assess the therapeutic response or disease risk, whole-lung …
matter to enter the body. To assess the therapeutic response or disease risk, whole-lung …
Multiscale Modeling of Respiratory Transport Phenomena and Intersubject Variability
SC Kassinos, J Sznitman - Annual Review of Fluid Mechanics, 2024 - annualreviews.org
Our understanding of respiratory flow phenomena has been consolidated over decades with
the exploration of in vitro and in silico canonical models that underscore the multiscale fluid …
the exploration of in vitro and in silico canonical models that underscore the multiscale fluid …
Predictors of Expiratory Flow Limitation during Exercise in Healthy Males and Females.
Y Molgat-Seon, PB Dominelli, CM Peters… - … and Science in …, 2022 - europepmc.org
Purpose This study aimed to determine which factors predispose individuals to EFL during
exercise and whether these factors differ based on sex. We hypothesized that i) EFL …
exercise and whether these factors differ based on sex. We hypothesized that i) EFL …
[HTML][HTML] Is the lung built for exercise? Advances and unresolved questions
CM Peters, JA Dempsey, SR Hopkins… - Medicine and science …, 2023 - pmc.ncbi.nlm.nih.gov
PETERS, CM, JA DEMPSEY, SR HOPKINS, and AW SHEEL. Is the Lung Built for Exercise?
Advances and Unresolved Questions. Med. Sci. Sports Exerc., Vol. 55, No. 12, pp. 2143 …
Advances and Unresolved Questions. Med. Sci. Sports Exerc., Vol. 55, No. 12, pp. 2143 …
Modelling approaches to particle deposition and clearance in the human respiratory tract
M Lazaridis - Air Quality, Atmosphere & Health, 2023 - Springer
Dosimetry models for the estimation of particle deposition in the human respiratory tract (RT)
in conjunction with clearance transport models are vital components to relate human …
in conjunction with clearance transport models are vital components to relate human …