The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

Systemic inflammation elicited by sepsis can induce an acute cerebral dysfunction known as
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …

The choroid plexus (CP) forming the blood–cerebrospinal fluid (B-CSF) barrier is among the
least studied structures of the central nervous system (CNS) despite its clinical importance …

An imbalance between remyelinating and demyelinating rates underlies degenerative
processes in demyelinating diseases such as multiple sclerosis. An optimal therapeutic …

Barriers between circulation and the central nervous system (CNS) play a key role in the
development and modulation of CNS immune responses. Structural variations in the …

Toll-like receptors (TLRs) are a group of receptors widely distributed in the organism. In the
central nervous system, they are expressed in neurons, astrocytes and microglia. Although …

Mental processes and their neural substrates are intimately linked to the homeostatic control
of internal bodily state. There are a set of distinct interoceptive pathways that directly and …

Microglial cells are the resident macrophages in the central nervous system. These cells of
mesodermal/mesenchymal origin migrate into all regions of the central nervous system …

Pattern recognition receptors (PRRs) are part of the innate immune response and were
originally discovered for their role in recognizing pathogens by ligating specific pathogen …

The aim of this study was to establish a link between periodontal disease and Alzheimer's
disease (AD) with a view to identifying the major periodontal disease bacteria (Treponema …