Neural substrates of the drift-diffusion model in brain disorders

A Gupta, R Bansal, H Alashwal, AS Kacar… - Frontiers in …, 2022 - frontiersin.org
Many studies on the drift-diffusion model (DDM) explain decision-making based on a unified
analysis of both accuracy and response times. This review provides an in-depth account of …

Are candidate neurocognitive endophenotypes of OCD present in paediatric patients? A systematic review

AA Marzuki, BJ Sahakian, TW Robbins - Neuroscience & Biobehavioral …, 2020 - Elsevier
To-date it has been difficult to ascertain the exact cognitive profile of childhood OCD as
studies report variable results. Adult OCD research lately utilises the endophenotype …

Obsessive–compulsive symptoms and information seeking during the Covid-19 pandemic

AM Loosen, V Skvortsova, TU Hauser - Translational psychiatry, 2021 - nature.com
Increased mental-health symptoms as a reaction to stressful life events, such as the Covid-
19 pandemic, are common. Critically, successful adaptation helps to reduce such symptoms …

Association of environmental uncertainty with altered decision-making and learning mechanisms in youths with obsessive-compulsive disorder

AA Marzuki, I Tomić, SHY Ip, J Gottwald… - JAMA network …, 2021 - jamanetwork.com
Importance Adults with obsessive-compulsive disorder (OCD) display perseverative
behavior in stable environments but exhibit vacillating choice when payoffs are uncertain …

Towards a computational psychiatry of juvenile obsessive-compulsive disorder

AM Loosen, TU Hauser - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Abstract Obsessive-Compulsive Disorder (OCD) most often emerges during adolescence,
but we know little about the aberrant neural and cognitive developmental mechanisms that …

A Meta-analytic study on executive function performance in children/adolescents with OCD

P López-Hernández, J Sánchez-Meca… - Anales de Psicología …, 2022 - revistas.um.es
Introducción: El objetivo general de este estudio fue llevar a cabo un estudio meta-analítico
con el fin de examinar el rendimiento de las funciones ejecutivas en niños/adolescentes con …

Compulsive avoidance in youths and adults with OCD: an aversive pavlovian-to-instrumental transfer study

AA Marzuki, P Banca, S Garofalo, LAE Degni… - Translational …, 2024 - nature.com
Compulsive behaviour may often be triggered by Pavlovian cues. Assessing how Pavlovian
cues drive instrumental behaviour in obsessive-compulsive disorder (OCD) is therefore …

On the development of OCD

TU Hauser - The Neurobiology and Treatment of OCD: Accelerating …, 2021 - Springer
OCD most often arises before adulthood with adolescence being a particularly vulnerable
period. This is also a time when both brain and cognition undergo fundamental …

Atypical action updating in a dynamic environment associated with adolescent obsessive–compulsive disorder

AA Marzuki, MM Vaghi… - Journal of Child …, 2022 - Wiley Online Library
Background Computational research had determined that adults with obsessive–compulsive
disorder (OCD) display heightened action updating in response to noise in the environment …

Characterizing the role of the pre‐SMA in the control of speed/accuracy trade‐off with directed functional connectivity mapping and multiple solution reduction

A Weigard, A Beltz, SN Reddy… - Human Brain …, 2019 - Wiley Online Library
Several plausible theories of the neural implementation of speed/accuracy trade‐off (SAT),
the phenomenon in which individuals may alternately emphasize speed or accuracy during …