In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …

Lipid based formulations (LBF) provide well proven opportunities to enhance the oral
absorption of drugs and drug candidates that sit close to, or beyond, the boundaries of …

Intestinal permeation enhancers (PEs) are one of the most widely tested strategies to
improve oral delivery of therapeutic peptides. This article assesses the intestinal permeation …

The development of oral dosage forms that allows absorption of therapeutic peptides to the
systemic circulation is one of the greatest challenges for the pharmaceutical industry …

This article is aimed to overview the lipid-based nanostructures designed so far for the oral
administration of peptides and proteins, and to analyze the influence of their composition …

The absorption of orally administered drug products is a complex, dynamic process,
dependant on a range of biopharmaceutical properties; notably the aqueous solubility of a …

Citric acid, a tricarboxylic acid, has found wide application in the chemical and
pharmaceutical industry due to its biocompatibility, versatility, and green, environmentally …

Bone is a connective tissue that support the entire body and protect the internal organs.
However, there are great challenges on curing intractable skeletal diseases such as …

Nontoxic materials with natural origin are promising materials in the designing and
preparation of the new drug delivery systems (DDSs). Today's, citric acid (CA) has attracted …

Due to excellent efficacy, low toxicity, and well-defined selectivity, development of new
injectable peptides is increasing. However, the translation of these drugs into products for …