Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review

G Muteeb, MT Rehman, M Shahwan, M Aatif - Pharmaceuticals, 2023 - mdpi.com
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

[HTML][HTML] Biofilms: Understanding the structure and contribution towards bacterial resistance in antibiotics

P Shree, CK Singh, KK Sodhi, JN Surya… - Medicine in …, 2023 - Elsevier
The biofilm is a bacterial colony wrapped in an auto-produced polymer matrix of
polysaccharides, proteins, and DNA. Bacterial biofilms cause persistent infections because …

Spatial mapping of mobile genetic elements and their bacterial hosts in complex microbiomes

B Grodner, H Shi, O Farchione, AC Vill, I Ntekas… - Nature …, 2024 - nature.com
The exchange of mobile genetic elements (MGEs) facilitates the spread of functional traits
including antimicrobial resistance within bacterial communities. Tools to spatially map MGEs …

Environmental impact and human health effects of polycyclic aromatic hydrocarbons and remedial strategies: a detailed review

G Venkatraman, N Giribabu, PS Mohan, B Muttiah… - Chemosphere, 2024 - Elsevier
Abstract Polycyclic Aromatic Hydrocarbons (PAHs) profoundly impact public and
environmental health. Gaining a comprehensive understanding of their intricate functions …

Mechanisms of antimicrobial resistance in biofilms

HY Liu, EL Prentice, MA Webber - npj Antimicrobials and Resistance, 2024 - nature.com
Most bacteria in nature exist in aggregated communities known as biofilms, and cells within
a biofilm demonstrate major physiological changes compared to their planktonic …

A growing battlefield in the war against biofilm-induced antimicrobial resistance: insights from reviews on antibiotic resistance

L Pai, S Patil, S Liu, F Wen - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Biofilms are a common survival strategy employed by bacteria in healthcare settings, which
enhances their resistance to antimicrobial and biocidal agents making infections difficult to …

Fighting polymicrobial biofilms in bacterial vaginosis

LGV Sousa, SA Pereira, N Cerca - Microbial Biotechnology, 2023 - Wiley Online Library
Bacterial vaginosis (BV) is the most common cause of vaginal discharge and is often
associated with other health consequences mainly in pregnant women. BV is described by …

Purification of aquaculture wastewater by macrophytes and biofilm systems: efficient removal of trace antibiotics and enrichment of antibiotic resistance genes

Z Ge, Z Ma, J Zou, Y Zhang, Y Li, L Zhang… - Science of the Total …, 2023 - Elsevier
The purification performance of aquaculture wastewater and the risk of antibiotic resistance
genes (ARGs) dissemination in wetlands dominated by macrophytes remain unclear. Here …

Advances on electrochemical disinfection research: Mechanisms, influencing factors and applications

Z Li, D Yang, S Li, L Yang, W Yan, H Xu - Science of The Total Environment, 2023 - Elsevier
Disinfection, a vital barrier against pathogenic microorganisms, is crucial in halting the
spread of waterborne diseases. Electrochemical methods have been extensively …

[HTML][HTML] Antibiotic resistant bacteria in food systems: Current status, resistance mechanisms, and mitigation strategies

SA Okaiyeto, PP Sutar, C Chen, JB Ni, J Wang… - Agriculture …, 2024 - Elsevier
The pervasive use of antibiotics in agriculture and animal husbandry has raised a significant
concern—residual antibiotic contamination in food, which contributes to the natural evolution …