Tumor cells use a wide variety of post-translational mechanisms to modify the functional
repertoire of their transcriptome. One emerging but still understudied mechanism involves …

Abnormal glycosylation due to dysregulated glycosyltransferases and glycosidases is a key
phenomenon of many malignancies, including colorectal cancer (CRC). In particular …

CD44 is an integral hyaluronan receptor that can promote or inhibit motogenic signaling in
tumor cells. Rhamm is a nonintegral cell surface hyaluronan receptor (CD168) and …

The oxidative damage of lipid, protein and DNA is known to be involved in chronic
inflammation as well as metastasis. It has been highlighted for searching natural compounds …

Background: Silibinin, a flavanone from milk thistle, inhibits the growth of tumors in several
rodent models. We examined the effects of dietary silibinin on the growth, progression, and …

Vascular endothelial growth factor (VEGF) is a potent mediator of angiogenesis which has
multiple effects in lung development and physiology. VEGF is expressed in several parts of …

Cell to cell adhesion is mediated by adhesion molecules present on the cell surface.
Downregulation of molecules that form the adhesion complex is a characteristic of metastatic …

Gastric cancer (GC) is a malignancy with few effective treatment options after metastasis
occurs. Quercetin (Qu) intake has been associated with reduced incidence and slow …

• Introduction• Stem cells and cancer stem cells‐Properties of stem cells‐Cancer stem cell
hypothesis• Development of pre‐cancerous and cancer stem cells‐Origin of pre‐cancerous …

Over the past few decades significant advances have been made in the development of
nanopharmaceuticals (including phospholipid and polymer-based therapeutics) against …