Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

For more than 70 years, glucocorticoids (GCs) have been a powerful and affordable
treatment option for inflammatory diseases. However, their benefits do not come without a …

Abstract A Dry Powder Inhaler (DPI) is a technique as well as a device used to inhale
formulation which is in the form of dry powder, and is inhaled through the nose or mouth. It …

Acetylcholinesterase inhibitors are the most used drugs to manage Alzheimer's disease,
although they show low bioavailability in the brain. In this sense, nasal administration has …

The nasal route has been used for many years for the local treatment of nasal diseases.
More recently, this route has been gaining momentum, due to the possibility of targeting the …

Powders for nasal delivery have been recognized as advantageous dosage forms over
liquids due to increased stability and residence time on nasal mucosa, with improved …

Abstract Blood-Brain Barrier (BBB) acts as a highly impermeable barrier, presenting an
impediment to the crossing of most classical drugs targeted for neurodegenerative diseases …

The nasal route has been investigated as a promising alternative for drug delivery to the
central nervous system, avoiding passage through the blood–brain barrier and improving …

The intranasal route has proven to be a reliable and promising route for delivering
therapeutics to the central nervous system (CNS), averting the blood–brain barrier (BBB) …

Introduction This work aimed to develop chitosan-coated cubosomal nanoparticles intended
for nose-to-brain delivery of paliperidone palmitate. They were compared with standard and …