Mitochondria are best known for harboring pathways involved in ATP synthesis through the
tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding …

Significance: Fluorescent protein sensors have revitalized the field of redox biology by
revolutionizing the study of redox processes in living cells and organisms. Recent Advances …

Impaired mitochondrial maintenance in disparate cell types is a shared hallmark of many
human pathologies and ageing,,,,,,,. How mitochondrial biogenesis coordinates with the …

The toxicity of misfolded proteins and mitochondrial dysfunction are pivotal factors that
promote age-associated functional neuronal decline and neurodegenerative disease …

Monitoring subcellular functional and structural changes associated with metabolism is
essential for understanding healthy tissue development and the progression of numerous …

Actively dividing cells, including some cancers, rely on aerobic glycolysis rather than
oxidative phosphorylation to generate energy, a phenomenon termed the Warburg effect …

In this work, we examine the relationship between stress resistance and aging. We find that
resistance to multiple types of stress peaks during early adulthood and then declines with …

A growing emphasis has been paid to the function of mitochondria in tumors,
neurodegenerative disorders (NDs), and cardiovascular diseases. Mitochondria are oxygen …

If mitochondria are the powerhouses of the cell, then mitochondrial dynamics are the power
grid that regulates how that energy output is directed and maintained in response to unique …

Fluctuations in oxygen (O2) concentrations represent a major challenge to aerobic
organisms and can be extremely damaging to their mitochondria. Marine intertidal molluscs …