[HTML][HTML] Osteoarthritis year in review 2020: epidemiology & therapy

G Peat, MJ Thomas - Osteoarthritis and cartilage, 2021 - Elsevier
This personal choice of research themes and highlights from within the past year (1 May
2019 to 14 April 2020) spans descriptive, analytical-observational, and intervention studies …

An evidence-based systematic review of human knee post-traumatic osteoarthritis (PTOA): timeline of clinical presentation and disease markers, comparison of knee …

CM Khella, R Asgarian, JM Horvath, B Rolauffs… - International Journal of …, 2021 - mdpi.com
Understanding the causality of the post-traumatic osteoarthritis (PTOA) disease process of
the knee joint is important for diagnosing early disease and developing new and effective …

Predicting anterior cruciate ligament reinjury from return-to-activity assessments at 6 months postsurgery: a prospective cohort study

SG Bodkin, J Hertel, DR Diduch… - Journal of athletic …, 2022 - meridian.allenpress.com
Context Return-to-activity (RTA) assessments are commonly administered after anterior
cruciate ligament reconstruction (ACLR) to manage the patient's postoperative progressions …

Environmental risk factors for osteoarthritis: The impact on individuals with knee joint injury

DM Werner, YM Golightly, M Tao… - Rheumatic …, 2022 - rheumatic.theclinics.com
Discussion Risk factors for the development and progression of early knee OA can be
broken into two categories: non-modifiable and modifiable (Table 1). Non-modifiable risk …

Post-traumatic osteoarthritis: a review of pathogenic mechanisms and novel targets for mitigation

JE Dilley, MA Bello, N Roman, T McKinley, U Sankar - Bone Reports, 2023 - Elsevier
Post-traumatic osteoarthritis (PTOA) develops secondary to a joint injury and accounts for
12% of all osteoarthritis. These injuries, often of the lower extremity joints, occur due to …

Targeted treatment for osteoarthritis: drugs and delivery system

L Mao, W Wu, M Wang, J Guo, H Li, S Zhang, J Xu… - Drug …, 2021 - Taylor & Francis
The management of osteoarthritis (OA) is a clinical challenge due to the particular avascular,
dense, and occluded tissue structure. Despite numerous clinical reports and animal studies …

Neuroplastic alterations in common synaptic inputs and synergistic motor unit clusters controlling the vastii muscles of individuals with ACL reconstruction

S Nuccio, CM Germer, A Casolo… - Journal of Applied …, 2024 - journals.physiology.org
This cross-sectional study aims to elucidate the neural mechanisms underlying the control of
knee extension forces in individuals with anterior cruciate ligament reconstruction (ACLR) …

The risk factors and preventive strategies of poor knee functions and osteoarthritis after anterior cruciate ligament reconstruction: a narrative review

IPGS Adhitya, I Kurniawati, R Sawa… - Physical Therapy …, 2023 - jstage.jst.go.jp
Anterior cruciate ligament reconstruction (ACLR) is the standard surgical treatment for ACL
injury, which typically uses a graft to replace the torn ligament in the knee that uses small …

Patient and operative risk factors for osteoarthritis after primary anterior cruciate ligament reconstruction: a cohort study of 41,976 patients

HA Prentice, PH Chan, EW Paxton… - … American Journal of …, 2024 - journals.sagepub.com
Background: The reported incidence of posttraumatic knee osteoarthritis (PTOA) after
primary anterior cruciate ligament reconstruction (ACLR) varies considerably. Further, there …

Epigenetic modification and exosome effects on autophagy in osteoarthritis

C Cheng, Y Wu, Y Huang, Q Xue, Y Wang… - Biochemical …, 2023 - Elsevier
Osteoarthritis (OA) is a degenerative disease that leads to joint pain and stiffness and is one
of the leading causes of disability and pain worldwide. Autophagy is a highly conserved self …